Coexistence of primary myelofibrosis and chronic lymphocytic leukemia

Sonja Burgstaller, Josef Thaler Klinikum Wels-Grieskirchen, Abteilung für Innere Medizin IV, Wels, AustriaAbstract: Coexistence of two hematologic malignancies in one patient is generally a rare phenomenon. The topic of this article is the coincidence of primary myelofibrosis and chronic l...

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Autores principales:	Burgstaller S, Thaler J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/f51f6e3cd9c741f59f55ae95c6592b23
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spelling	oai:doaj.org-article:f51f6e3cd9c741f59f55ae95c6592b232021-12-02T00:12:54ZCoexistence of primary myelofibrosis and chronic lymphocytic leukemia1179-9889https://doaj.org/article/f51f6e3cd9c741f59f55ae95c6592b232014-10-01T00:00:00Zhttp://www.dovepress.com/coexistence-of-primary-myelofibrosis-and-chronic-lymphocytic-leukemia-peer-reviewed-article-BLCTThttps://doaj.org/toc/1179-9889 Sonja Burgstaller, Josef Thaler Klinikum Wels-Grieskirchen, Abteilung für Innere Medizin IV, Wels, AustriaAbstract: Coexistence of two hematologic malignancies in one patient is generally a rare phenomenon. The topic of this article is the coincidence of primary myelofibrosis and chronic lymphocytic leukemia, which has been reported up to now in only 16 patients. In summary, simultaneous detection of both diseases was notable in half of the patients at presentation. In the case of a subsequent diagnosis of both disorders, primary myelofibrosis preceded the lymphoproliferative disease in the majority of patients. The clinical course seems to be more benign than for each disorder itself. A substantial proportion of patients did not require any treatment at all. Knowledge about the pathogenetic mechanisms, treatment approaches, and prognosis of these patients is limited.Keywords: primary myelofibrosis, chronic lymphocytic leukemia, coexistentBurgstaller SThaler JDove Medical PressarticleDiseases of the blood and blood-forming organsRC633-647.5ENBlood and Lymphatic Cancer: Targets and Therapy, Vol 2014, Iss default, Pp 101-105 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	Diseases of the blood and blood-forming organs RC633-647.5 Burgstaller S Thaler J Coexistence of primary myelofibrosis and chronic lymphocytic leukemia
description	Sonja Burgstaller, Josef Thaler Klinikum Wels-Grieskirchen, Abteilung für Innere Medizin IV, Wels, AustriaAbstract: Coexistence of two hematologic malignancies in one patient is generally a rare phenomenon. The topic of this article is the coincidence of primary myelofibrosis and chronic lymphocytic leukemia, which has been reported up to now in only 16 patients. In summary, simultaneous detection of both diseases was notable in half of the patients at presentation. In the case of a subsequent diagnosis of both disorders, primary myelofibrosis preceded the lymphoproliferative disease in the majority of patients. The clinical course seems to be more benign than for each disorder itself. A substantial proportion of patients did not require any treatment at all. Knowledge about the pathogenetic mechanisms, treatment approaches, and prognosis of these patients is limited.Keywords: primary myelofibrosis, chronic lymphocytic leukemia, coexistent
format	article
author	Burgstaller S Thaler J
author_facet	Burgstaller S Thaler J
author_sort	Burgstaller S
title	Coexistence of primary myelofibrosis and chronic lymphocytic leukemia
title_short	Coexistence of primary myelofibrosis and chronic lymphocytic leukemia
title_full	Coexistence of primary myelofibrosis and chronic lymphocytic leukemia
title_fullStr	Coexistence of primary myelofibrosis and chronic lymphocytic leukemia
title_full_unstemmed	Coexistence of primary myelofibrosis and chronic lymphocytic leukemia
title_sort	coexistence of primary myelofibrosis and chronic lymphocytic leukemia
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/f51f6e3cd9c741f59f55ae95c6592b23
work_keys_str_mv	AT burgstallers coexistenceofprimarymyelofibrosisandchroniclymphocyticleukemia AT thalerj coexistenceofprimarymyelofibrosisandchroniclymphocyticleukemia
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Coexistence of primary myelofibrosis and chronic lymphocytic leukemia

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