Poly (Orange CD) sensor for paracetamol in presence of folic acid and dopamine

Abstract In the present work, Orange CD was chosen as an intriguing modifier for the electropolymerization on the surface of CPE by the CV technique. A novel, sensitive, and cost-effective poly (Orange CD) MCPE (PoOCD/MCPE) sensor was utilized for the selective detection of paracetamol (PA) in 0.2 M...

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Autores principales:	S. D. Sukanya, B. E. Kumara Swamy, J. K. Shashikumara, S. C. Sharma, S. A. Hariprasad
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f525a067d15743269efca80c49950ffb
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spelling	oai:doaj.org-article:f525a067d15743269efca80c49950ffb2021-11-21T12:24:06ZPoly (Orange CD) sensor for paracetamol in presence of folic acid and dopamine10.1038/s41598-021-01311-52045-2322https://doaj.org/article/f525a067d15743269efca80c49950ffb2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01311-5https://doaj.org/toc/2045-2322Abstract In the present work, Orange CD was chosen as an intriguing modifier for the electropolymerization on the surface of CPE by the CV technique. A novel, sensitive, and cost-effective poly (Orange CD) MCPE (PoOCD/MCPE) sensor was utilized for the selective detection of paracetamol (PA) in 0.2 M phosphate buffer solution (PBS) of pH 7.4. The oxidation peak current of PA was vastly enhanced at the sensor. The scan rate study is suggested that electro-oxidation of PA was adsorption-controlled. The pH study testifies the redox pathways transport with the same quantity of electrons and protons. The detection limit of PA is found to be 2.64 µM. DPV results show that substantial peak separation between PA, folic acid (FA), and dopamine (DA) could be facilitating their individual and simultaneous determination on the sensor. The decorated sensor demonstrates high sensitivity, stability, reproducibility, repeatability and has been successfully exploited for the detection of PA in a tablet with promising results.S. D. SukanyaB. E. Kumara SwamyJ. K. ShashikumaraS. C. SharmaS. A. HariprasadNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q S. D. Sukanya B. E. Kumara Swamy J. K. Shashikumara S. C. Sharma S. A. Hariprasad Poly (Orange CD) sensor for paracetamol in presence of folic acid and dopamine
description	Abstract In the present work, Orange CD was chosen as an intriguing modifier for the electropolymerization on the surface of CPE by the CV technique. A novel, sensitive, and cost-effective poly (Orange CD) MCPE (PoOCD/MCPE) sensor was utilized for the selective detection of paracetamol (PA) in 0.2 M phosphate buffer solution (PBS) of pH 7.4. The oxidation peak current of PA was vastly enhanced at the sensor. The scan rate study is suggested that electro-oxidation of PA was adsorption-controlled. The pH study testifies the redox pathways transport with the same quantity of electrons and protons. The detection limit of PA is found to be 2.64 µM. DPV results show that substantial peak separation between PA, folic acid (FA), and dopamine (DA) could be facilitating their individual and simultaneous determination on the sensor. The decorated sensor demonstrates high sensitivity, stability, reproducibility, repeatability and has been successfully exploited for the detection of PA in a tablet with promising results.
format	article
author	S. D. Sukanya B. E. Kumara Swamy J. K. Shashikumara S. C. Sharma S. A. Hariprasad
author_facet	S. D. Sukanya B. E. Kumara Swamy J. K. Shashikumara S. C. Sharma S. A. Hariprasad
author_sort	S. D. Sukanya
title	Poly (Orange CD) sensor for paracetamol in presence of folic acid and dopamine
title_short	Poly (Orange CD) sensor for paracetamol in presence of folic acid and dopamine
title_full	Poly (Orange CD) sensor for paracetamol in presence of folic acid and dopamine
title_fullStr	Poly (Orange CD) sensor for paracetamol in presence of folic acid and dopamine
title_full_unstemmed	Poly (Orange CD) sensor for paracetamol in presence of folic acid and dopamine
title_sort	poly (orange cd) sensor for paracetamol in presence of folic acid and dopamine
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f525a067d15743269efca80c49950ffb
work_keys_str_mv	AT sdsukanya polyorangecdsensorforparacetamolinpresenceoffolicacidanddopamine AT bekumaraswamy polyorangecdsensorforparacetamolinpresenceoffolicacidanddopamine AT jkshashikumara polyorangecdsensorforparacetamolinpresenceoffolicacidanddopamine AT scsharma polyorangecdsensorforparacetamolinpresenceoffolicacidanddopamine AT sahariprasad polyorangecdsensorforparacetamolinpresenceoffolicacidanddopamine
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Poly (Orange CD) sensor for paracetamol in presence of folic acid and dopamine

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