Strong Association of Angiotensin Converting Enzyme-2 Gene Insertion/Deletion Polymorphism with Susceptibility to SARS-CoV-2, Hypertension, Coronary Artery Disease and COVID-19 Disease Mortality

Strong Association of Angiotensin Converting Enzyme-2 Gene Insertion/Deletion Polymorphism with Susceptibility to SARS-CoV-2, Hypertension, Coronary Artery Disease and COVID-19 Disease Mortality

Background: The ongoing outbreak of SARS-CoV-2 represents a significant challenge to international health. Several reports have highlighted the importance of ACE2 on the pathogenesis of COVID-19. The spike protein of SARS-CoV-2 efficiently binds to the angiotensin-converting enzyme 2 (ACE2) receptor...

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Bibliographic Details
Main Authors: Mohammad Muzaffar Mir, Rashid Mir, Mushabab Ayed Abdullah Alghamdi, Badr Abdulmohsin Alsayed, Javed Iqbal Wani, Muffarah Hamid Alharthi, Abdullah M. AL-Shahrani
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
gene polymorphism
infection
SARS-CoV-2
COVID-19
pathogenesis
ACE1-angiotensin-converting enzyme 1
Medicine
R
Online Access:https://doaj.org/article/f52639dcefd44b4eaae09b177fb6e1a4
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