Altitude and risk of sudden unexpected infant death in the United States

Abstract The effect of altitude on the risk of sudden infant death syndrome (SIDS) has been reported previously, but with conflicting findings. We aimed to examine whether the risk of sudden unexpected infant death (SUID) varies with altitude in the United States. Data from the Centers for Disease C...

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Autores principales:	Richard Johnston, Xiaohan Yan, Tatiana M. Anderson, Edwin A. Mitchell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f52bae88e21c4cec8278a8ab08030a84
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spelling	oai:doaj.org-article:f52bae88e21c4cec8278a8ab08030a842021-12-02T13:57:49ZAltitude and risk of sudden unexpected infant death in the United States10.1038/s41598-021-81613-w2045-2322https://doaj.org/article/f52bae88e21c4cec8278a8ab08030a842021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-81613-whttps://doaj.org/toc/2045-2322Abstract The effect of altitude on the risk of sudden infant death syndrome (SIDS) has been reported previously, but with conflicting findings. We aimed to examine whether the risk of sudden unexpected infant death (SUID) varies with altitude in the United States. Data from the Centers for Disease Control and Prevention (CDC)’s Cohort Linked Birth/Infant Death Data Set for births between 2005 and 2010 were examined. County of birth was used to estimate altitude. Logistic regression and Generalized Additive Model (GAM) were used, adjusting for year, mother’s race, Hispanic origin, marital status, age, education and smoking, father’s age and race, number of prenatal visits, plurality, live birth order, and infant’s sex, birthweight and gestation. There were 25,305,778 live births over the 6-year study period. The total number of deaths from SUID in this period were 23,673 (rate = 0.94/1000 live births). In the logistic regression model there was a small, but statistically significant, increased risk of SUID associated with birth at > 8000 feet compared with < 6000 feet (aOR = 1.93; 95% CI 1.00–3.71). The GAM showed a similar increased risk over 8000 feet, but this was not statistically significant. Only 9245 (0.037%) of mothers gave birth at > 8000 feet during the study period and 10 deaths (0.042%) were attributed to SUID. The number of SUID deaths at this altitude in the United States is very small (10 deaths in 6 years).Richard JohnstonXiaohan YanTatiana M. AndersonEdwin A. MitchellNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Richard Johnston Xiaohan Yan Tatiana M. Anderson Edwin A. Mitchell Altitude and risk of sudden unexpected infant death in the United States
description	Abstract The effect of altitude on the risk of sudden infant death syndrome (SIDS) has been reported previously, but with conflicting findings. We aimed to examine whether the risk of sudden unexpected infant death (SUID) varies with altitude in the United States. Data from the Centers for Disease Control and Prevention (CDC)’s Cohort Linked Birth/Infant Death Data Set for births between 2005 and 2010 were examined. County of birth was used to estimate altitude. Logistic regression and Generalized Additive Model (GAM) were used, adjusting for year, mother’s race, Hispanic origin, marital status, age, education and smoking, father’s age and race, number of prenatal visits, plurality, live birth order, and infant’s sex, birthweight and gestation. There were 25,305,778 live births over the 6-year study period. The total number of deaths from SUID in this period were 23,673 (rate = 0.94/1000 live births). In the logistic regression model there was a small, but statistically significant, increased risk of SUID associated with birth at > 8000 feet compared with < 6000 feet (aOR = 1.93; 95% CI 1.00–3.71). The GAM showed a similar increased risk over 8000 feet, but this was not statistically significant. Only 9245 (0.037%) of mothers gave birth at > 8000 feet during the study period and 10 deaths (0.042%) were attributed to SUID. The number of SUID deaths at this altitude in the United States is very small (10 deaths in 6 years).
format	article
author	Richard Johnston Xiaohan Yan Tatiana M. Anderson Edwin A. Mitchell
author_facet	Richard Johnston Xiaohan Yan Tatiana M. Anderson Edwin A. Mitchell
author_sort	Richard Johnston
title	Altitude and risk of sudden unexpected infant death in the United States
title_short	Altitude and risk of sudden unexpected infant death in the United States
title_full	Altitude and risk of sudden unexpected infant death in the United States
title_fullStr	Altitude and risk of sudden unexpected infant death in the United States
title_full_unstemmed	Altitude and risk of sudden unexpected infant death in the United States
title_sort	altitude and risk of sudden unexpected infant death in the united states
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f52bae88e21c4cec8278a8ab08030a84
work_keys_str_mv	AT richardjohnston altitudeandriskofsuddenunexpectedinfantdeathintheunitedstates AT xiaohanyan altitudeandriskofsuddenunexpectedinfantdeathintheunitedstates AT tatianamanderson altitudeandriskofsuddenunexpectedinfantdeathintheunitedstates AT edwinamitchell altitudeandriskofsuddenunexpectedinfantdeathintheunitedstates
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Altitude and risk of sudden unexpected infant death in the United States

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