AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells
Previously, we discovered that 1-(3,5-dimethoxyphenyl)-3-(4-(3-methoxyphenoxy)-2-((4-morpholinophenyl)amino)pyrimidin-5-yl)urea (AKF-D52), a synthetic phenoxypyrimidine urea derivative, acts as a growth inhibitor of various cancer cell types. In this study, we elucidated the antiproliferative proper...
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Autores principales: | Hyo-Sun Gil, Jeong-Hun Lee, Ahmed K. Farag, Ahmed H. E. Hassan, Kyung-Sook Chung, Jung-Hye Choi, Eun-Joo Roh, Kyung-Tae Lee |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/f52f7ce6b4b14e9ca8f82f05b51cd34c |
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