EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice

Ska1 is a kinetochore-localised protein that couples kinetochore movement to microtubule (MT) depolymerisation. Here Thomas et al. show that the MT +TIP binding protein EB1 recruits Ska1 to the MT-kinetochore interface and stabilises the interaction between Ska1 and MTs.

Guardado en:

Detalles Bibliográficos
Autores principales:	Geethu E. Thomas, K. Bandopadhyay, Sabyasachi Sutradhar, M. R. Renjith, Puja Singh, K. K. Gireesh, Steny Simon, Binshad Badarudeen, Hindol Gupta, Manidipa Banerjee, Raja Paul, J. Mitra, Tapas K. Manna
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f53440769de3492a93c9e28514a15bd5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f53440769de3492a93c9e28514a15bd5
record_format	dspace
spelling	oai:doaj.org-article:f53440769de3492a93c9e28514a15bd52021-12-02T16:58:23ZEB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice10.1038/ncomms116652041-1723https://doaj.org/article/f53440769de3492a93c9e28514a15bd52016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11665https://doaj.org/toc/2041-1723Ska1 is a kinetochore-localised protein that couples kinetochore movement to microtubule (MT) depolymerisation. Here Thomas et al. show that the MT +TIP binding protein EB1 recruits Ska1 to the MT-kinetochore interface and stabilises the interaction between Ska1 and MTs.Geethu E. ThomasK. BandopadhyaySabyasachi SutradharM. R. RenjithPuja SinghK. K. GireeshSteny SimonBinshad BadarudeenHindol GuptaManidipa BanerjeeRaja PaulJ. MitraTapas K. MannaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Geethu E. Thomas K. Bandopadhyay Sabyasachi Sutradhar M. R. Renjith Puja Singh K. K. Gireesh Steny Simon Binshad Badarudeen Hindol Gupta Manidipa Banerjee Raja Paul J. Mitra Tapas K. Manna EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice
description	Ska1 is a kinetochore-localised protein that couples kinetochore movement to microtubule (MT) depolymerisation. Here Thomas et al. show that the MT +TIP binding protein EB1 recruits Ska1 to the MT-kinetochore interface and stabilises the interaction between Ska1 and MTs.
format	article
author	Geethu E. Thomas K. Bandopadhyay Sabyasachi Sutradhar M. R. Renjith Puja Singh K. K. Gireesh Steny Simon Binshad Badarudeen Hindol Gupta Manidipa Banerjee Raja Paul J. Mitra Tapas K. Manna
author_facet	Geethu E. Thomas K. Bandopadhyay Sabyasachi Sutradhar M. R. Renjith Puja Singh K. K. Gireesh Steny Simon Binshad Badarudeen Hindol Gupta Manidipa Banerjee Raja Paul J. Mitra Tapas K. Manna
author_sort	Geethu E. Thomas
title	EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice
title_short	EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice
title_full	EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice
title_fullStr	EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice
title_full_unstemmed	EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice
title_sort	eb1 regulates attachment of ska1 with microtubules by forming extended structures on the microtubule lattice
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f53440769de3492a93c9e28514a15bd5
work_keys_str_mv	AT geethuethomas eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT kbandopadhyay eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT sabyasachisutradhar eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT mrrenjith eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT pujasingh eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT kkgireesh eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT stenysimon eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT binshadbadarudeen eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT hindolgupta eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT manidipabanerjee eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT rajapaul eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT jmitra eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice AT tapaskmanna eb1regulatesattachmentofska1withmicrotubulesbyformingextendedstructuresonthemicrotubulelattice
_version_	1718382365008461824

EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice

Ejemplares similares