EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice

EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice

Ska1 is a kinetochore-localised protein that couples kinetochore movement to microtubule (MT) depolymerisation. Here Thomas et al. show that the MT +TIP binding protein EB1 recruits Ska1 to the MT-kinetochore interface and stabilises the interaction between Ska1 and MTs.

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Detalles Bibliográficos
Autores principales: Geethu E. Thomas, K. Bandopadhyay, Sabyasachi Sutradhar, M. R. Renjith, Puja Singh, K. K. Gireesh, Steny Simon, Binshad Badarudeen, Hindol Gupta, Manidipa Banerjee, Raja Paul, J. Mitra, Tapas K. Manna
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/f53440769de3492a93c9e28514a15bd5
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