Transiently antigen-primed B cells return to naive-like state in absence of T-cell help

B-cell encounter with antigen is thought to result in anergy, cell death, or a productive B-cell response. Here the authors show that transient antigen acquisition can enable B-cell recruitment into productive responses or a return to a naive-like state, depending on availability of T-cell help.

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Bibliographic Details
Main Authors: Jackson S. Turner, Matangi Marthi, Zachary L. Benet, Irina Grigorova
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/f53888cf35a4452bb69b4220e56eaacc
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