The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention

Inflammation and nutrition as main factors can affect the prognosis of patients with chronic total coronary occlusion (CTO) undergoing percutaneous coronary intervention (PCI). The C-reactive protein to albumin ratio (CAR) can clarify the inflammation and nutrition status, which are highly related t...

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Autores principales:	Lele Cheng, Zixuan Meng, Qi Wang, Zhijie Jian, Pengcheng Fan, Xinxin Feng, Xiangrui Qiao, Jian Yang, Zuyi Yuan, Bolin Li, Yue Wu
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	c-reactive protein to albumin ratio percutaneous coronary intervention chronic coronary total occlusion adverse cardiovascular events prognostic indicator Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/f53c7d14f9cc48c8950ef2bd6cc07bba
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spelling	oai:doaj.org-article:f53c7d14f9cc48c8950ef2bd6cc07bba2021-11-17T18:45:51ZThe Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention2297-055X10.3389/fcvm.2021.731261https://doaj.org/article/f53c7d14f9cc48c8950ef2bd6cc07bba2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcvm.2021.731261/fullhttps://doaj.org/toc/2297-055XInflammation and nutrition as main factors can affect the prognosis of patients with chronic total coronary occlusion (CTO) undergoing percutaneous coronary intervention (PCI). The C-reactive protein to albumin ratio (CAR) can clarify the inflammation and nutrition status, which are highly related to clinical outcomes. This study aims to investigate the association between CAR and adverse cardiovascular events in patients with CTO undergoing PCI. For this study, 664 patients were divided into three groups based on the tertiles of CAR. The primary endpoint was all-cause mortality and the secondary endpoint was major adverse cardiovascular events (MACE). Over a median follow-up of 33.7 months, the primary endpoint occurred in 64 patients (9.6%) and the secondary endpoint occurred in 170 patients (25.6%). The patients with higher CAR represented a worse prognosis with all-cause death and cardiovascular death after the adjustment for the baseline risk factors. Adding the CAR values raised the predictive value for the incidence of the all-cause death and cardiovascular death but not MACE. The capacity of prognosis prediction was improved after the addition of the CAR value to the traditional prediction model.Lele ChengLele ChengLele ChengLele ChengZixuan MengQi WangZhijie JianPengcheng FanXinxin FengXiangrui QiaoXiangrui QiaoXiangrui QiaoJian YangZuyi YuanZuyi YuanZuyi YuanBolin LiBolin LiBolin LiYue WuFrontiers Media S.A.articlec-reactive protein to albumin ratiopercutaneous coronary interventionchronic coronary total occlusionadverse cardiovascular eventsprognostic indicatorDiseases of the circulatory (Cardiovascular) systemRC666-701ENFrontiers in Cardiovascular Medicine, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	c-reactive protein to albumin ratio percutaneous coronary intervention chronic coronary total occlusion adverse cardiovascular events prognostic indicator Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	c-reactive protein to albumin ratio percutaneous coronary intervention chronic coronary total occlusion adverse cardiovascular events prognostic indicator Diseases of the circulatory (Cardiovascular) system RC666-701 Lele Cheng Lele Cheng Lele Cheng Lele Cheng Zixuan Meng Qi Wang Zhijie Jian Pengcheng Fan Xinxin Feng Xiangrui Qiao Xiangrui Qiao Xiangrui Qiao Jian Yang Zuyi Yuan Zuyi Yuan Zuyi Yuan Bolin Li Bolin Li Bolin Li Yue Wu The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
description	Inflammation and nutrition as main factors can affect the prognosis of patients with chronic total coronary occlusion (CTO) undergoing percutaneous coronary intervention (PCI). The C-reactive protein to albumin ratio (CAR) can clarify the inflammation and nutrition status, which are highly related to clinical outcomes. This study aims to investigate the association between CAR and adverse cardiovascular events in patients with CTO undergoing PCI. For this study, 664 patients were divided into three groups based on the tertiles of CAR. The primary endpoint was all-cause mortality and the secondary endpoint was major adverse cardiovascular events (MACE). Over a median follow-up of 33.7 months, the primary endpoint occurred in 64 patients (9.6%) and the secondary endpoint occurred in 170 patients (25.6%). The patients with higher CAR represented a worse prognosis with all-cause death and cardiovascular death after the adjustment for the baseline risk factors. Adding the CAR values raised the predictive value for the incidence of the all-cause death and cardiovascular death but not MACE. The capacity of prognosis prediction was improved after the addition of the CAR value to the traditional prediction model.
format	article
author	Lele Cheng Lele Cheng Lele Cheng Lele Cheng Zixuan Meng Qi Wang Zhijie Jian Pengcheng Fan Xinxin Feng Xiangrui Qiao Xiangrui Qiao Xiangrui Qiao Jian Yang Zuyi Yuan Zuyi Yuan Zuyi Yuan Bolin Li Bolin Li Bolin Li Yue Wu
author_facet	Lele Cheng Lele Cheng Lele Cheng Lele Cheng Zixuan Meng Qi Wang Zhijie Jian Pengcheng Fan Xinxin Feng Xiangrui Qiao Xiangrui Qiao Xiangrui Qiao Jian Yang Zuyi Yuan Zuyi Yuan Zuyi Yuan Bolin Li Bolin Li Bolin Li Yue Wu
author_sort	Lele Cheng
title	The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_short	The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_full	The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_fullStr	The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_full_unstemmed	The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention
title_sort	usefulness of c-reactive protein to albumin ratio in the prediction of adverse cardiovascular events in coronary chronic total occlusion undergoing percutaneous coronary intervention
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/f53c7d14f9cc48c8950ef2bd6cc07bba
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The Usefulness of C-Reactive Protein to Albumin Ratio in the Prediction of Adverse Cardiovascular Events in Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention

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