Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland.

Infective endocarditis (IE) is associated with high mortality. However, data on factors associated with length of stay (LOS) in hospital due to IE are scarce. In addition, long-term mortality of more than 1 year is inadequately known. In this large population-based study we investigated age and sex...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Elina Ahtela, Jarmo Oksi, Tero Vahlberg, Jussi Sipilä, Päivi Rautava, Ville Kytö
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f54178f9bfd74d9ca77ba98e5b9f542f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f54178f9bfd74d9ca77ba98e5b9f542f
record_format	dspace
spelling	oai:doaj.org-article:f54178f9bfd74d9ca77ba98e5b9f542f2021-12-02T20:09:10ZShort- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland.1932-620310.1371/journal.pone.0254553https://doaj.org/article/f54178f9bfd74d9ca77ba98e5b9f542f2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0254553https://doaj.org/toc/1932-6203Infective endocarditis (IE) is associated with high mortality. However, data on factors associated with length of stay (LOS) in hospital due to IE are scarce. In addition, long-term mortality of more than 1 year is inadequately known. In this large population-based study we investigated age and sex differences, temporal trends, and factors affecting the LOS in patients with IE and in-hospital, 1-year, 5-year and 10-year mortality of IE. Data on patients (≥18 years of age) admitted to hospital due to IE in Finland during 2005-2014 were collected retrospectively from nationwide obligatory registries. We included 2166 patients in our study. Of the patients 67.8% were men. Women were older than men (mean age 63.3 vs. 59.5, p<0.001). The median LOS was 20.0 days in men and 18.0 in women, p = 0.015. In the youngest patients (18-39 years) the median LOS was significantly longer than in the oldest patients (≥80 years) (24.0 vs. 16.0 days, p = 0.014). In-hospital mortality was 10% with no difference between men and women. Mortality was 22.7% at 1 year whereas 5- and 10-year mortality was 37.5% and 48.5%, respectively. The 5-year and 10-year mortality was higher in women (HR 1.18, p = 0.034; HR 1.18, p = 0.021). Both in-hospital and long-term mortality increased significantly with aging and comorbidity burden. Both mortality and LOS remained stable over the study period. In conclusion, men had longer hospital stays due to IE compared to women. The 5- and 10-year mortality was higher in women. The mortality of IE or LOS did not change over time.Elina AhtelaJarmo OksiTero VahlbergJussi SipiläPäivi RautavaVille KytöPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 7, p e0254553 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Elina Ahtela Jarmo Oksi Tero Vahlberg Jussi Sipilä Päivi Rautava Ville Kytö Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland.
description	Infective endocarditis (IE) is associated with high mortality. However, data on factors associated with length of stay (LOS) in hospital due to IE are scarce. In addition, long-term mortality of more than 1 year is inadequately known. In this large population-based study we investigated age and sex differences, temporal trends, and factors affecting the LOS in patients with IE and in-hospital, 1-year, 5-year and 10-year mortality of IE. Data on patients (≥18 years of age) admitted to hospital due to IE in Finland during 2005-2014 were collected retrospectively from nationwide obligatory registries. We included 2166 patients in our study. Of the patients 67.8% were men. Women were older than men (mean age 63.3 vs. 59.5, p<0.001). The median LOS was 20.0 days in men and 18.0 in women, p = 0.015. In the youngest patients (18-39 years) the median LOS was significantly longer than in the oldest patients (≥80 years) (24.0 vs. 16.0 days, p = 0.014). In-hospital mortality was 10% with no difference between men and women. Mortality was 22.7% at 1 year whereas 5- and 10-year mortality was 37.5% and 48.5%, respectively. The 5-year and 10-year mortality was higher in women (HR 1.18, p = 0.034; HR 1.18, p = 0.021). Both in-hospital and long-term mortality increased significantly with aging and comorbidity burden. Both mortality and LOS remained stable over the study period. In conclusion, men had longer hospital stays due to IE compared to women. The 5- and 10-year mortality was higher in women. The mortality of IE or LOS did not change over time.
format	article
author	Elina Ahtela Jarmo Oksi Tero Vahlberg Jussi Sipilä Päivi Rautava Ville Kytö
author_facet	Elina Ahtela Jarmo Oksi Tero Vahlberg Jussi Sipilä Päivi Rautava Ville Kytö
author_sort	Elina Ahtela
title	Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland.
title_short	Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland.
title_full	Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland.
title_fullStr	Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland.
title_full_unstemmed	Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland.
title_sort	short- and long-term outcomes of infective endocarditis admission in adults: a population-based registry study in finland.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/f54178f9bfd74d9ca77ba98e5b9f542f
work_keys_str_mv	AT elinaahtela shortandlongtermoutcomesofinfectiveendocarditisadmissioninadultsapopulationbasedregistrystudyinfinland AT jarmooksi shortandlongtermoutcomesofinfectiveendocarditisadmissioninadultsapopulationbasedregistrystudyinfinland AT terovahlberg shortandlongtermoutcomesofinfectiveendocarditisadmissioninadultsapopulationbasedregistrystudyinfinland AT jussisipila shortandlongtermoutcomesofinfectiveendocarditisadmissioninadultsapopulationbasedregistrystudyinfinland AT paivirautava shortandlongtermoutcomesofinfectiveendocarditisadmissioninadultsapopulationbasedregistrystudyinfinland AT villekyto shortandlongtermoutcomesofinfectiveendocarditisadmissioninadultsapopulationbasedregistrystudyinfinland
_version_	1718375159356719104

Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland.

Ejemplares similares