PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION

Abstract. Results of cytokine network studies system in children with rotavirus infection are presented. Concentrations of cytokines were determined at both local and systemic levels. Analysis of cytokine levels was performed at initial terms (day 1 to 3), and in the course of disease (day 7 to 10)....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	S. N. Benyova, Ye. M. Zhidkov, Ye. V. Markelova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	cytokines rotavirus infection th1 th2 children Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/f5505ab5e532441b811d4372651c2437
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f5505ab5e532441b811d4372651c2437
record_format	dspace
spelling	oai:doaj.org-article:f5505ab5e532441b811d4372651c24372021-11-18T08:03:39ZPATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION1563-06252313-741X10.15789/1563-0625-2007-6-627-630https://doaj.org/article/f5505ab5e532441b811d4372651c24372014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/250https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Results of cytokine network studies system in children with rotavirus infection are presented. Concentrations of cytokines were determined at both local and systemic levels. Analysis of cytokine levels was performed at initial terms (day 1 to 3), and in the course of disease (day 7 to 10). It was revealed that mild and mid-severe cases of rotavirus infection in the children are characterized by early increase in proinflammatory cytokines with restricted overshoot of proinflammatory cytokines at early recovery period. Meanwhile, the patients with severe forms of viral gastroenteritis exhibited high levels of proinflammatory cytokines. However, this balance was shifted towards anti-inflammatory cytokines during early reconvalescence.S. N. BenyovaYe. M. ZhidkovYe. V. MarkelovaSPb RAACIarticlecytokinesrotavirus infectionth1th2childrenImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 6, Pp 627-630 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	cytokines rotavirus infection th1 th2 children Immunologic diseases. Allergy RC581-607
spellingShingle	cytokines rotavirus infection th1 th2 children Immunologic diseases. Allergy RC581-607 S. N. Benyova Ye. M. Zhidkov Ye. V. Markelova PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION
description	Abstract. Results of cytokine network studies system in children with rotavirus infection are presented. Concentrations of cytokines were determined at both local and systemic levels. Analysis of cytokine levels was performed at initial terms (day 1 to 3), and in the course of disease (day 7 to 10). It was revealed that mild and mid-severe cases of rotavirus infection in the children are characterized by early increase in proinflammatory cytokines with restricted overshoot of proinflammatory cytokines at early recovery period. Meanwhile, the patients with severe forms of viral gastroenteritis exhibited high levels of proinflammatory cytokines. However, this balance was shifted towards anti-inflammatory cytokines during early reconvalescence.
format	article
author	S. N. Benyova Ye. M. Zhidkov Ye. V. Markelova
author_facet	S. N. Benyova Ye. M. Zhidkov Ye. V. Markelova
author_sort	S. N. Benyova
title	PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION
title_short	PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION
title_full	PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION
title_fullStr	PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION
title_full_unstemmed	PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION
title_sort	pathogenetic role of cytokines in childhood rotavirus infection
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/f5505ab5e532441b811d4372651c2437
work_keys_str_mv	AT snbenyova pathogeneticroleofcytokinesinchildhoodrotavirusinfection AT yemzhidkov pathogeneticroleofcytokinesinchildhoodrotavirusinfection AT yevmarkelova pathogeneticroleofcytokinesinchildhoodrotavirusinfection
_version_	1718422580220657664

PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION

Ejemplares similares