Structural basis of ECF-σ-factor-dependent transcription initiation

No structural data have been available for RNA polymerase holoenzymes or transcription initiation complexes that contain extracytoplasmic σ factors. Here the authors report the crystal structures of transcription initiation complexes comprising Mycobacterium tuberculosis RNA polymerase, extracytopla...

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Autores principales:	Wei Lin, Sukhendu Mandal, David Degen, Min Sung Cho, Yu Feng, Kalyan Das, Richard H. Ebright
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f55e90aaf41f47288c3b2ad96204bc88
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spelling	oai:doaj.org-article:f55e90aaf41f47288c3b2ad96204bc882021-12-02T16:58:02ZStructural basis of ECF-σ-factor-dependent transcription initiation10.1038/s41467-019-08443-32041-1723https://doaj.org/article/f55e90aaf41f47288c3b2ad96204bc882019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08443-3https://doaj.org/toc/2041-1723No structural data have been available for RNA polymerase holoenzymes or transcription initiation complexes that contain extracytoplasmic σ factors. Here the authors report the crystal structures of transcription initiation complexes comprising Mycobacterium tuberculosis RNA polymerase, extracytoplasmic σ factor σL and promoter DNA.Wei LinSukhendu MandalDavid DegenMin Sung ChoYu FengKalyan DasRichard H. EbrightNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei Lin Sukhendu Mandal David Degen Min Sung Cho Yu Feng Kalyan Das Richard H. Ebright Structural basis of ECF-σ-factor-dependent transcription initiation
description	No structural data have been available for RNA polymerase holoenzymes or transcription initiation complexes that contain extracytoplasmic σ factors. Here the authors report the crystal structures of transcription initiation complexes comprising Mycobacterium tuberculosis RNA polymerase, extracytoplasmic σ factor σL and promoter DNA.
format	article
author	Wei Lin Sukhendu Mandal David Degen Min Sung Cho Yu Feng Kalyan Das Richard H. Ebright
author_facet	Wei Lin Sukhendu Mandal David Degen Min Sung Cho Yu Feng Kalyan Das Richard H. Ebright
author_sort	Wei Lin
title	Structural basis of ECF-σ-factor-dependent transcription initiation
title_short	Structural basis of ECF-σ-factor-dependent transcription initiation
title_full	Structural basis of ECF-σ-factor-dependent transcription initiation
title_fullStr	Structural basis of ECF-σ-factor-dependent transcription initiation
title_full_unstemmed	Structural basis of ECF-σ-factor-dependent transcription initiation
title_sort	structural basis of ecf-σ-factor-dependent transcription initiation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/f55e90aaf41f47288c3b2ad96204bc88
work_keys_str_mv	AT weilin structuralbasisofecfsfactordependenttranscriptioninitiation AT sukhendumandal structuralbasisofecfsfactordependenttranscriptioninitiation AT daviddegen structuralbasisofecfsfactordependenttranscriptioninitiation AT minsungcho structuralbasisofecfsfactordependenttranscriptioninitiation AT yufeng structuralbasisofecfsfactordependenttranscriptioninitiation AT kalyandas structuralbasisofecfsfactordependenttranscriptioninitiation AT richardhebright structuralbasisofecfsfactordependenttranscriptioninitiation
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Structural basis of ECF-σ-factor-dependent transcription initiation

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