New optical coherence tomography fundus findings in a case of beta-thalassemia

MI Eleftheriadou,1 PG Theodossiadis,1 A Rouvas,1 D Alonistiotis,1 GP Theodossiadis212nd Department of Ophthalmology,&rdquo;Attikon&rdquo; University Hospital, University of Athens, 2Department of Ophthalmology, &ldquo;Henry Dunant&rdquo; Hospital, Athens, GreeceAbstra...

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Autores principales:	Eleftheriadou MI, Theodossiadis PG, Rouvas A, Alonistiotis D, Theodossiadis GP
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f56bb8490ac440af958cb39313fdc92a
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spelling	oai:doaj.org-article:f56bb8490ac440af958cb39313fdc92a2021-12-02T01:43:43ZNew optical coherence tomography fundus findings in a case of beta-thalassemia1177-54671177-5483https://doaj.org/article/f56bb8490ac440af958cb39313fdc92a2012-12-01T00:00:00Zhttp://www.dovepress.com/new-optical-coherence-tomography-fundus-findings-in-a-case-of-beta-tha-a11795https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483MI Eleftheriadou,1 PG Theodossiadis,1 A Rouvas,1 D Alonistiotis,1 GP Theodossiadis212nd Department of Ophthalmology,&rdquo;Attikon&rdquo; University Hospital, University of Athens, 2Department of Ophthalmology, &ldquo;Henry Dunant&rdquo; Hospital, Athens, GreeceAbstract: Patients with beta-thalassemia may present with an acquired diffuse elastic tissue defect due to degeneration of elastic tissue along with vaso-occlusive findings in the retinal microvasculature. Here we report the case of a patient with granular-like accumulation presenting as black sunburst lesions detected by optical coherence tomography (OCT). A 38-year-old man with beta-thalassemia intermedia associated with angioid streaks complained of deterioration of vision in both eyes. Funduscopic examination revealed small, round, hyperpigmented lesions bilaterally. During the early and late phases of fluorescein angiography, granular hyperfluoresence was present, associated with pigment decompensation and mottled-like hypofluorescence. The main OCT finding was the presence of granuloid-like accumulations at the retinal pigment epithelium level. Granule penetration was also noticed at the photoreceptor layer, while isolated granuloid-like accumulations were found in the inner layers of the macula and choroid. In this case, the new OCT finding was the granular-like hyperpigmented accumulations in the macula located at the level of the retinal pigment epithelium. To the best of our knowledge, our OCT findings show for the first time granuloid-like accumulations representing black sunburst lesions.Keywords: beta-thalassemia, angioid streaks, optical coherence tomography, granuloid-like accumulation, retinal pigment epitheliumEleftheriadou MITheodossiadis PGRouvas AAlonistiotis DTheodossiadis GPDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 2119-2122 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Eleftheriadou MI Theodossiadis PG Rouvas A Alonistiotis D Theodossiadis GP New optical coherence tomography fundus findings in a case of beta-thalassemia
description	MI Eleftheriadou,1 PG Theodossiadis,1 A Rouvas,1 D Alonistiotis,1 GP Theodossiadis212nd Department of Ophthalmology,&rdquo;Attikon&rdquo; University Hospital, University of Athens, 2Department of Ophthalmology, &ldquo;Henry Dunant&rdquo; Hospital, Athens, GreeceAbstract: Patients with beta-thalassemia may present with an acquired diffuse elastic tissue defect due to degeneration of elastic tissue along with vaso-occlusive findings in the retinal microvasculature. Here we report the case of a patient with granular-like accumulation presenting as black sunburst lesions detected by optical coherence tomography (OCT). A 38-year-old man with beta-thalassemia intermedia associated with angioid streaks complained of deterioration of vision in both eyes. Funduscopic examination revealed small, round, hyperpigmented lesions bilaterally. During the early and late phases of fluorescein angiography, granular hyperfluoresence was present, associated with pigment decompensation and mottled-like hypofluorescence. The main OCT finding was the presence of granuloid-like accumulations at the retinal pigment epithelium level. Granule penetration was also noticed at the photoreceptor layer, while isolated granuloid-like accumulations were found in the inner layers of the macula and choroid. In this case, the new OCT finding was the granular-like hyperpigmented accumulations in the macula located at the level of the retinal pigment epithelium. To the best of our knowledge, our OCT findings show for the first time granuloid-like accumulations representing black sunburst lesions.Keywords: beta-thalassemia, angioid streaks, optical coherence tomography, granuloid-like accumulation, retinal pigment epithelium
format	article
author	Eleftheriadou MI Theodossiadis PG Rouvas A Alonistiotis D Theodossiadis GP
author_facet	Eleftheriadou MI Theodossiadis PG Rouvas A Alonistiotis D Theodossiadis GP
author_sort	Eleftheriadou MI
title	New optical coherence tomography fundus findings in a case of beta-thalassemia
title_short	New optical coherence tomography fundus findings in a case of beta-thalassemia
title_full	New optical coherence tomography fundus findings in a case of beta-thalassemia
title_fullStr	New optical coherence tomography fundus findings in a case of beta-thalassemia
title_full_unstemmed	New optical coherence tomography fundus findings in a case of beta-thalassemia
title_sort	new optical coherence tomography fundus findings in a case of beta-thalassemia
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/f56bb8490ac440af958cb39313fdc92a
work_keys_str_mv	AT eleftheriadoumi newopticalcoherencetomographyfundusfindingsinacaseofbetathalassemia AT theodossiadispg newopticalcoherencetomographyfundusfindingsinacaseofbetathalassemia AT rouvasa newopticalcoherencetomographyfundusfindingsinacaseofbetathalassemia AT alonistiotisd newopticalcoherencetomographyfundusfindingsinacaseofbetathalassemia AT theodossiadisgp newopticalcoherencetomographyfundusfindingsinacaseofbetathalassemia
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New optical coherence tomography fundus findings in a case of beta-thalassemia

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