Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA

Cells infected with Epstein-Barr virus (EBV) express the virus-encoded EBNA1, which is essential for viral genome maintenance but also highly antigenic. Here the authors implicate nucleolin as a host factor that mediates the repression of EBNA1-derived antigenic peptides through binding of the G4-qu...

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Autores principales:	María José Lista, Rodrigo Prado Martins, Olivier Billant, Marie-Astrid Contesse, Sarah Findakly, Pierre Pochard, Chrysoula Daskalogianni, Claire Beauvineau, Corinne Guetta, Christophe Jamin, Marie-Paule Teulade-Fichou, Robin Fåhraeus, Cécile Voisset, Marc Blondel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f56cd55b90034b299ee5f01fcf9bb0d5
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spelling	oai:doaj.org-article:f56cd55b90034b299ee5f01fcf9bb0d52021-12-02T14:40:25ZNucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA10.1038/ncomms160432041-1723https://doaj.org/article/f56cd55b90034b299ee5f01fcf9bb0d52017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms16043https://doaj.org/toc/2041-1723Cells infected with Epstein-Barr virus (EBV) express the virus-encoded EBNA1, which is essential for viral genome maintenance but also highly antigenic. Here the authors implicate nucleolin as a host factor that mediates the repression of EBNA1-derived antigenic peptides through binding of the G4-quadruplex structure present within the EBNA1 mRNA.María José ListaRodrigo Prado MartinsOlivier BillantMarie-Astrid ContesseSarah FindaklyPierre PochardChrysoula DaskalogianniClaire BeauvineauCorinne GuettaChristophe JaminMarie-Paule Teulade-FichouRobin FåhraeusCécile VoissetMarc BlondelNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q María José Lista Rodrigo Prado Martins Olivier Billant Marie-Astrid Contesse Sarah Findakly Pierre Pochard Chrysoula Daskalogianni Claire Beauvineau Corinne Guetta Christophe Jamin Marie-Paule Teulade-Fichou Robin Fåhraeus Cécile Voisset Marc Blondel Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
description	Cells infected with Epstein-Barr virus (EBV) express the virus-encoded EBNA1, which is essential for viral genome maintenance but also highly antigenic. Here the authors implicate nucleolin as a host factor that mediates the repression of EBNA1-derived antigenic peptides through binding of the G4-quadruplex structure present within the EBNA1 mRNA.
format	article
author	María José Lista Rodrigo Prado Martins Olivier Billant Marie-Astrid Contesse Sarah Findakly Pierre Pochard Chrysoula Daskalogianni Claire Beauvineau Corinne Guetta Christophe Jamin Marie-Paule Teulade-Fichou Robin Fåhraeus Cécile Voisset Marc Blondel
author_facet	María José Lista Rodrigo Prado Martins Olivier Billant Marie-Astrid Contesse Sarah Findakly Pierre Pochard Chrysoula Daskalogianni Claire Beauvineau Corinne Guetta Christophe Jamin Marie-Paule Teulade-Fichou Robin Fåhraeus Cécile Voisset Marc Blondel
author_sort	María José Lista
title	Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
title_short	Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
title_full	Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
title_fullStr	Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
title_full_unstemmed	Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
title_sort	nucleolin directly mediates epstein-barr virus immune evasion through binding to g-quadruplexes of ebna1 mrna
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f56cd55b90034b299ee5f01fcf9bb0d5
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Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA

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