Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors

The laterodorsal tegmental nucleus (LDT) is known to influence reward processing through its projections to the VTA. Here, the authors report that the cholinergic projections from the LDT to the nucleus accumbens play an important role in motivation and positive reinforcement behaviors.

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Auteurs principaux: Bárbara Coimbra, Carina Soares-Cunha, Nivaldo A P Vasconcelos, Ana Verónica Domingues, Sónia Borges, Nuno Sousa, Ana João Rodrigues
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/f56df6bde61a4e5f9efc8b868a43fe57
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Résumé:The laterodorsal tegmental nucleus (LDT) is known to influence reward processing through its projections to the VTA. Here, the authors report that the cholinergic projections from the LDT to the nucleus accumbens play an important role in motivation and positive reinforcement behaviors.