Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors

The laterodorsal tegmental nucleus (LDT) is known to influence reward processing through its projections to the VTA. Here, the authors report that the cholinergic projections from the LDT to the nucleus accumbens play an important role in motivation and positive reinforcement behaviors.

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Autores principales: Bárbara Coimbra, Carina Soares-Cunha, Nivaldo A P Vasconcelos, Ana Verónica Domingues, Sónia Borges, Nuno Sousa, Ana João Rodrigues
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f56df6bde61a4e5f9efc8b868a43fe57
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spelling oai:doaj.org-article:f56df6bde61a4e5f9efc8b868a43fe572021-12-02T15:36:20ZRole of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors10.1038/s41467-019-11557-32041-1723https://doaj.org/article/f56df6bde61a4e5f9efc8b868a43fe572019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11557-3https://doaj.org/toc/2041-1723The laterodorsal tegmental nucleus (LDT) is known to influence reward processing through its projections to the VTA. Here, the authors report that the cholinergic projections from the LDT to the nucleus accumbens play an important role in motivation and positive reinforcement behaviors.Bárbara CoimbraCarina Soares-CunhaNivaldo A P VasconcelosAna Verónica DominguesSónia BorgesNuno SousaAna João RodriguesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bárbara Coimbra
Carina Soares-Cunha
Nivaldo A P Vasconcelos
Ana Verónica Domingues
Sónia Borges
Nuno Sousa
Ana João Rodrigues
Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
description The laterodorsal tegmental nucleus (LDT) is known to influence reward processing through its projections to the VTA. Here, the authors report that the cholinergic projections from the LDT to the nucleus accumbens play an important role in motivation and positive reinforcement behaviors.
format article
author Bárbara Coimbra
Carina Soares-Cunha
Nivaldo A P Vasconcelos
Ana Verónica Domingues
Sónia Borges
Nuno Sousa
Ana João Rodrigues
author_facet Bárbara Coimbra
Carina Soares-Cunha
Nivaldo A P Vasconcelos
Ana Verónica Domingues
Sónia Borges
Nuno Sousa
Ana João Rodrigues
author_sort Bárbara Coimbra
title Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_short Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_full Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_fullStr Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_full_unstemmed Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_sort role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/f56df6bde61a4e5f9efc8b868a43fe57
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