Peroxisomal Membrane Contact Sites in Yeasts

Peroxisomes are ubiquitous, single membrane-bound organelles that play a crucial role in lipid metabolism and human health. While peroxisome number is maintained by the division of existing peroxisomes, nascent peroxisomes can be generated from the endoplasmic reticulum (ER) membrane in yeasts. Duri...

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Autor principal: Amit S. Joshi
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/f58abdc9586a47deb1b2b0f2ff0defec
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spelling oai:doaj.org-article:f58abdc9586a47deb1b2b0f2ff0defec2021-11-19T07:07:25ZPeroxisomal Membrane Contact Sites in Yeasts2296-634X10.3389/fcell.2021.735031https://doaj.org/article/f58abdc9586a47deb1b2b0f2ff0defec2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcell.2021.735031/fullhttps://doaj.org/toc/2296-634XPeroxisomes are ubiquitous, single membrane-bound organelles that play a crucial role in lipid metabolism and human health. While peroxisome number is maintained by the division of existing peroxisomes, nascent peroxisomes can be generated from the endoplasmic reticulum (ER) membrane in yeasts. During formation and proliferation, peroxisomes maintain membrane contacts with the ER. In addition to the ER, contacts between peroxisomes and other organelles such as lipid droplets, mitochondria, vacuole, and plasma membrane have been reported. These membrane contact sites (MCS) are dynamic and important for cellular function. This review focuses on the recent developments in peroxisome biogenesis and the functional importance of peroxisomal MCS in yeasts.Amit S. JoshiFrontiers Media S.A.articlemembrane contact sitesperoxisomesorganelleslipid dropletmitochondriaendoplasmic reticulumBiology (General)QH301-705.5ENFrontiers in Cell and Developmental Biology, Vol 9 (2021)
institution DOAJ
collection DOAJ
language EN
topic membrane contact sites
peroxisomes
organelles
lipid droplet
mitochondria
endoplasmic reticulum
Biology (General)
QH301-705.5
spellingShingle membrane contact sites
peroxisomes
organelles
lipid droplet
mitochondria
endoplasmic reticulum
Biology (General)
QH301-705.5
Amit S. Joshi
Peroxisomal Membrane Contact Sites in Yeasts
description Peroxisomes are ubiquitous, single membrane-bound organelles that play a crucial role in lipid metabolism and human health. While peroxisome number is maintained by the division of existing peroxisomes, nascent peroxisomes can be generated from the endoplasmic reticulum (ER) membrane in yeasts. During formation and proliferation, peroxisomes maintain membrane contacts with the ER. In addition to the ER, contacts between peroxisomes and other organelles such as lipid droplets, mitochondria, vacuole, and plasma membrane have been reported. These membrane contact sites (MCS) are dynamic and important for cellular function. This review focuses on the recent developments in peroxisome biogenesis and the functional importance of peroxisomal MCS in yeasts.
format article
author Amit S. Joshi
author_facet Amit S. Joshi
author_sort Amit S. Joshi
title Peroxisomal Membrane Contact Sites in Yeasts
title_short Peroxisomal Membrane Contact Sites in Yeasts
title_full Peroxisomal Membrane Contact Sites in Yeasts
title_fullStr Peroxisomal Membrane Contact Sites in Yeasts
title_full_unstemmed Peroxisomal Membrane Contact Sites in Yeasts
title_sort peroxisomal membrane contact sites in yeasts
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/f58abdc9586a47deb1b2b0f2ff0defec
work_keys_str_mv AT amitsjoshi peroxisomalmembranecontactsitesinyeasts
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