Spleen-resident CD4+ and CD4- CD8α- dendritic cell subsets differ in their ability to prime invariant natural killer T lymphocytes.

Spleen-resident CD4+ and CD4- CD8α- dendritic cell subsets differ in their ability to prime invariant natural killer T lymphocytes.

One important function of conventional dendritic cells (cDC) is their high capacity to capture, process and present Ag to T lymphocytes. Mouse splenic cDC subtypes, including CD8α(+) and CD8α(-) cDC, are not identical in their Ag presenting and T cell priming functions. Surprisingly, few studies hav...

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Autores principales: Emilie Bialecki, Elodie Macho Fernandez, Stoyan Ivanov, Christophe Paget, Josette Fontaine, Fabien Rodriguez, Luc Lebeau, Christophe Ehret, Benoit Frisch, François Trottein, Christelle Faveeuw
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/f592492316654cba9c521e333a8dc5e3
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