Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters

Seth D Norrholm1,2, Tanja Jovanovic21Atlanta VA Medical Center, Mental Health Service Line, Decatur, GA, USA; 2Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USAAbstract: According to the Diagnostic and Statistical Manual of Mental Disorders, 4th...

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Autores principales: Seth D Norrholm, Tanja Jovanovic
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Lenguaje:EN
Publicado: Dove Medical Press 2010
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Acceso en línea:https://doaj.org/article/f599f1ae14664711982639503fda4b45
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spelling oai:doaj.org-article:f599f1ae14664711982639503fda4b452021-12-02T00:12:50ZTailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters1176-63281178-2021https://doaj.org/article/f599f1ae14664711982639503fda4b452010-08-01T00:00:00Zhttp://www.dovepress.com/tailoring-therapeutic-strategies-for-treating-posttraumatic-stress-dis-a5100https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Seth D Norrholm1,2, Tanja Jovanovic21Atlanta VA Medical Center, Mental Health Service Line, Decatur, GA, USA; 2Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USAAbstract: According to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, posttraumatic stress disorder (PTSD) is characterized by three major symptom clusters following an event that elicited fear, helplessness, or horror. This review will examine each symptom cluster of PTSD separately, giving case study examples of patients who exhibit a preponderance of a given symptom domain. We use a translational approach in describing the underlying neurobiology that is relevant to particular symptoms and treatment options, thus showing how clinical practice can benefit from current research. By focusing on symptom clusters, we provide a more specific view of individual patient’s clinical presentations, in order to better address treatment needs. Finally, the review will also address potential genetic approaches to treatment as another form of individualized treatment.Keywords: psychophysiology, pharmacotherapy, exposure therapy, pharmacogenetics; posttraumatic stress disorder, symptom clusters Seth D NorrholmTanja JovanovicDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2010, Iss Issue 1, Pp 517-532 (2010)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Seth D Norrholm
Tanja Jovanovic
Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters
description Seth D Norrholm1,2, Tanja Jovanovic21Atlanta VA Medical Center, Mental Health Service Line, Decatur, GA, USA; 2Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USAAbstract: According to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, posttraumatic stress disorder (PTSD) is characterized by three major symptom clusters following an event that elicited fear, helplessness, or horror. This review will examine each symptom cluster of PTSD separately, giving case study examples of patients who exhibit a preponderance of a given symptom domain. We use a translational approach in describing the underlying neurobiology that is relevant to particular symptoms and treatment options, thus showing how clinical practice can benefit from current research. By focusing on symptom clusters, we provide a more specific view of individual patient’s clinical presentations, in order to better address treatment needs. Finally, the review will also address potential genetic approaches to treatment as another form of individualized treatment.Keywords: psychophysiology, pharmacotherapy, exposure therapy, pharmacogenetics; posttraumatic stress disorder, symptom clusters
format article
author Seth D Norrholm
Tanja Jovanovic
author_facet Seth D Norrholm
Tanja Jovanovic
author_sort Seth D Norrholm
title Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters
title_short Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters
title_full Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters
title_fullStr Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters
title_full_unstemmed Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters
title_sort tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters
publisher Dove Medical Press
publishDate 2010
url https://doaj.org/article/f599f1ae14664711982639503fda4b45
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