Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters
Seth D Norrholm1,2, Tanja Jovanovic21Atlanta VA Medical Center, Mental Health Service Line, Decatur, GA, USA; 2Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USAAbstract: According to the Diagnostic and Statistical Manual of Mental Disorders, 4th...
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Dove Medical Press
2010
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oai:doaj.org-article:f599f1ae14664711982639503fda4b452021-12-02T00:12:50ZTailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters1176-63281178-2021https://doaj.org/article/f599f1ae14664711982639503fda4b452010-08-01T00:00:00Zhttp://www.dovepress.com/tailoring-therapeutic-strategies-for-treating-posttraumatic-stress-dis-a5100https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Seth D Norrholm1,2, Tanja Jovanovic21Atlanta VA Medical Center, Mental Health Service Line, Decatur, GA, USA; 2Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USAAbstract: According to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, posttraumatic stress disorder (PTSD) is characterized by three major symptom clusters following an event that elicited fear, helplessness, or horror. This review will examine each symptom cluster of PTSD separately, giving case study examples of patients who exhibit a preponderance of a given symptom domain. We use a translational approach in describing the underlying neurobiology that is relevant to particular symptoms and treatment options, thus showing how clinical practice can benefit from current research. By focusing on symptom clusters, we provide a more specific view of individual patient’s clinical presentations, in order to better address treatment needs. Finally, the review will also address potential genetic approaches to treatment as another form of individualized treatment.Keywords: psychophysiology, pharmacotherapy, exposure therapy, pharmacogenetics; posttraumatic stress disorder, symptom clusters Seth D NorrholmTanja JovanovicDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2010, Iss Issue 1, Pp 517-532 (2010) |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Seth D Norrholm Tanja Jovanovic Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters |
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Seth D Norrholm1,2, Tanja Jovanovic21Atlanta VA Medical Center, Mental Health Service Line, Decatur, GA, USA; 2Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USAAbstract: According to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, posttraumatic stress disorder (PTSD) is characterized by three major symptom clusters following an event that elicited fear, helplessness, or horror. This review will examine each symptom cluster of PTSD separately, giving case study examples of patients who exhibit a preponderance of a given symptom domain. We use a translational approach in describing the underlying neurobiology that is relevant to particular symptoms and treatment options, thus showing how clinical practice can benefit from current research. By focusing on symptom clusters, we provide a more specific view of individual patient’s clinical presentations, in order to better address treatment needs. Finally, the review will also address potential genetic approaches to treatment as another form of individualized treatment.Keywords: psychophysiology, pharmacotherapy, exposure therapy, pharmacogenetics; posttraumatic stress disorder, symptom clusters |
format |
article |
author |
Seth D Norrholm Tanja Jovanovic |
author_facet |
Seth D Norrholm Tanja Jovanovic |
author_sort |
Seth D Norrholm |
title |
Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters |
title_short |
Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters |
title_full |
Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters |
title_fullStr |
Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters |
title_full_unstemmed |
Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters |
title_sort |
tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters |
publisher |
Dove Medical Press |
publishDate |
2010 |
url |
https://doaj.org/article/f599f1ae14664711982639503fda4b45 |
work_keys_str_mv |
AT sethdnorrholm tailoringtherapeuticstrategiesfortreatingposttraumaticstressdisordersymptomclusters AT tanjajovanovic tailoringtherapeuticstrategiesfortreatingposttraumaticstressdisordersymptomclusters |
_version_ |
1718403899922055168 |