DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty

Intravenous illicit drug use (IDU) and hepatitis C infection (HCV) often occur among HIV-infected individuals. Here, the authors report an epigenome-wide association analysis of IDU and HCV in HIV-infected individuals, finding that their associated methylation signatures inform HIV frailty.

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Autores principales: Xinyu Zhang, Ying Hu, Amy C Justice, Boyang Li, Zuoheng Wang, Hongyu Zhao, John H Krystal, Ke Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f59d61ac0ae14c6a946423923b595b79
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spelling oai:doaj.org-article:f59d61ac0ae14c6a946423923b595b792021-12-02T14:40:46ZDNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty10.1038/s41467-017-02326-12041-1723https://doaj.org/article/f59d61ac0ae14c6a946423923b595b792017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02326-1https://doaj.org/toc/2041-1723Intravenous illicit drug use (IDU) and hepatitis C infection (HCV) often occur among HIV-infected individuals. Here, the authors report an epigenome-wide association analysis of IDU and HCV in HIV-infected individuals, finding that their associated methylation signatures inform HIV frailty.Xinyu ZhangYing HuAmy C JusticeBoyang LiZuoheng WangHongyu ZhaoJohn H KrystalKe XuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xinyu Zhang
Ying Hu
Amy C Justice
Boyang Li
Zuoheng Wang
Hongyu Zhao
John H Krystal
Ke Xu
DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty
description Intravenous illicit drug use (IDU) and hepatitis C infection (HCV) often occur among HIV-infected individuals. Here, the authors report an epigenome-wide association analysis of IDU and HCV in HIV-infected individuals, finding that their associated methylation signatures inform HIV frailty.
format article
author Xinyu Zhang
Ying Hu
Amy C Justice
Boyang Li
Zuoheng Wang
Hongyu Zhao
John H Krystal
Ke Xu
author_facet Xinyu Zhang
Ying Hu
Amy C Justice
Boyang Li
Zuoheng Wang
Hongyu Zhao
John H Krystal
Ke Xu
author_sort Xinyu Zhang
title DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty
title_short DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty
title_full DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty
title_fullStr DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty
title_full_unstemmed DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty
title_sort dna methylation signatures of illicit drug injection and hepatitis c are associated with hiv frailty
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/f59d61ac0ae14c6a946423923b595b79
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