DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty
Intravenous illicit drug use (IDU) and hepatitis C infection (HCV) often occur among HIV-infected individuals. Here, the authors report an epigenome-wide association analysis of IDU and HCV in HIV-infected individuals, finding that their associated methylation signatures inform HIV frailty.
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Nature Portfolio
2017
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oai:doaj.org-article:f59d61ac0ae14c6a946423923b595b792021-12-02T14:40:46ZDNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty10.1038/s41467-017-02326-12041-1723https://doaj.org/article/f59d61ac0ae14c6a946423923b595b792017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02326-1https://doaj.org/toc/2041-1723Intravenous illicit drug use (IDU) and hepatitis C infection (HCV) often occur among HIV-infected individuals. Here, the authors report an epigenome-wide association analysis of IDU and HCV in HIV-infected individuals, finding that their associated methylation signatures inform HIV frailty.Xinyu ZhangYing HuAmy C JusticeBoyang LiZuoheng WangHongyu ZhaoJohn H KrystalKe XuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q Xinyu Zhang Ying Hu Amy C Justice Boyang Li Zuoheng Wang Hongyu Zhao John H Krystal Ke Xu DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty |
description |
Intravenous illicit drug use (IDU) and hepatitis C infection (HCV) often occur among HIV-infected individuals. Here, the authors report an epigenome-wide association analysis of IDU and HCV in HIV-infected individuals, finding that their associated methylation signatures inform HIV frailty. |
format |
article |
author |
Xinyu Zhang Ying Hu Amy C Justice Boyang Li Zuoheng Wang Hongyu Zhao John H Krystal Ke Xu |
author_facet |
Xinyu Zhang Ying Hu Amy C Justice Boyang Li Zuoheng Wang Hongyu Zhao John H Krystal Ke Xu |
author_sort |
Xinyu Zhang |
title |
DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty |
title_short |
DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty |
title_full |
DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty |
title_fullStr |
DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty |
title_full_unstemmed |
DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty |
title_sort |
dna methylation signatures of illicit drug injection and hepatitis c are associated with hiv frailty |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/f59d61ac0ae14c6a946423923b595b79 |
work_keys_str_mv |
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1718390210549514240 |