Retention of paternal DNA methylome in the developing zebrafish germline
Germ cells are the means of transferring genetic information to the next generation. Here the authors characterise the DNA methylomes of zebrafish primordial germ cells and find that, unlike mammals, the zebrafish germ cells do not undergo genome-wide DNA demethylation but rather retain paternal DNA...
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Nature Portfolio
2019
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oai:doaj.org-article:f5ad45bf28cb41f8a8d95e38f494f2dc2021-12-02T15:35:08ZRetention of paternal DNA methylome in the developing zebrafish germline10.1038/s41467-019-10895-62041-1723https://doaj.org/article/f5ad45bf28cb41f8a8d95e38f494f2dc2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10895-6https://doaj.org/toc/2041-1723Germ cells are the means of transferring genetic information to the next generation. Here the authors characterise the DNA methylomes of zebrafish primordial germ cells and find that, unlike mammals, the zebrafish germ cells do not undergo genome-wide DNA demethylation but rather retain paternal DNA methylation patternsKsenia SkvortsovaKatsiaryna TarbashevichMartin StehlingRyan ListerManuel IrimiaErez RazOzren BogdanovicNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Ksenia Skvortsova Katsiaryna Tarbashevich Martin Stehling Ryan Lister Manuel Irimia Erez Raz Ozren Bogdanovic Retention of paternal DNA methylome in the developing zebrafish germline |
description |
Germ cells are the means of transferring genetic information to the next generation. Here the authors characterise the DNA methylomes of zebrafish primordial germ cells and find that, unlike mammals, the zebrafish germ cells do not undergo genome-wide DNA demethylation but rather retain paternal DNA methylation patterns |
format |
article |
author |
Ksenia Skvortsova Katsiaryna Tarbashevich Martin Stehling Ryan Lister Manuel Irimia Erez Raz Ozren Bogdanovic |
author_facet |
Ksenia Skvortsova Katsiaryna Tarbashevich Martin Stehling Ryan Lister Manuel Irimia Erez Raz Ozren Bogdanovic |
author_sort |
Ksenia Skvortsova |
title |
Retention of paternal DNA methylome in the developing zebrafish germline |
title_short |
Retention of paternal DNA methylome in the developing zebrafish germline |
title_full |
Retention of paternal DNA methylome in the developing zebrafish germline |
title_fullStr |
Retention of paternal DNA methylome in the developing zebrafish germline |
title_full_unstemmed |
Retention of paternal DNA methylome in the developing zebrafish germline |
title_sort |
retention of paternal dna methylome in the developing zebrafish germline |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/f5ad45bf28cb41f8a8d95e38f494f2dc |
work_keys_str_mv |
AT kseniaskvortsova retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline AT katsiarynatarbashevich retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline AT martinstehling retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline AT ryanlister retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline AT manuelirimia retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline AT erezraz retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline AT ozrenbogdanovic retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline |
_version_ |
1718386694963593216 |