Retention of paternal DNA methylome in the developing zebrafish germline

Germ cells are the means of transferring genetic information to the next generation. Here the authors characterise the DNA methylomes of zebrafish primordial germ cells and find that, unlike mammals, the zebrafish germ cells do not undergo genome-wide DNA demethylation but rather retain paternal DNA...

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Autores principales: Ksenia Skvortsova, Katsiaryna Tarbashevich, Martin Stehling, Ryan Lister, Manuel Irimia, Erez Raz, Ozren Bogdanovic
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f5ad45bf28cb41f8a8d95e38f494f2dc
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spelling oai:doaj.org-article:f5ad45bf28cb41f8a8d95e38f494f2dc2021-12-02T15:35:08ZRetention of paternal DNA methylome in the developing zebrafish germline10.1038/s41467-019-10895-62041-1723https://doaj.org/article/f5ad45bf28cb41f8a8d95e38f494f2dc2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10895-6https://doaj.org/toc/2041-1723Germ cells are the means of transferring genetic information to the next generation. Here the authors characterise the DNA methylomes of zebrafish primordial germ cells and find that, unlike mammals, the zebrafish germ cells do not undergo genome-wide DNA demethylation but rather retain paternal DNA methylation patternsKsenia SkvortsovaKatsiaryna TarbashevichMartin StehlingRyan ListerManuel IrimiaErez RazOzren BogdanovicNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ksenia Skvortsova
Katsiaryna Tarbashevich
Martin Stehling
Ryan Lister
Manuel Irimia
Erez Raz
Ozren Bogdanovic
Retention of paternal DNA methylome in the developing zebrafish germline
description Germ cells are the means of transferring genetic information to the next generation. Here the authors characterise the DNA methylomes of zebrafish primordial germ cells and find that, unlike mammals, the zebrafish germ cells do not undergo genome-wide DNA demethylation but rather retain paternal DNA methylation patterns
format article
author Ksenia Skvortsova
Katsiaryna Tarbashevich
Martin Stehling
Ryan Lister
Manuel Irimia
Erez Raz
Ozren Bogdanovic
author_facet Ksenia Skvortsova
Katsiaryna Tarbashevich
Martin Stehling
Ryan Lister
Manuel Irimia
Erez Raz
Ozren Bogdanovic
author_sort Ksenia Skvortsova
title Retention of paternal DNA methylome in the developing zebrafish germline
title_short Retention of paternal DNA methylome in the developing zebrafish germline
title_full Retention of paternal DNA methylome in the developing zebrafish germline
title_fullStr Retention of paternal DNA methylome in the developing zebrafish germline
title_full_unstemmed Retention of paternal DNA methylome in the developing zebrafish germline
title_sort retention of paternal dna methylome in the developing zebrafish germline
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/f5ad45bf28cb41f8a8d95e38f494f2dc
work_keys_str_mv AT kseniaskvortsova retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline
AT katsiarynatarbashevich retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline
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AT ryanlister retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline
AT manuelirimia retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline
AT erezraz retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline
AT ozrenbogdanovic retentionofpaternaldnamethylomeinthedevelopingzebrafishgermline
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