Prevalence of Celiac Disease in Type 1 Diabetic Children and adolescents in East Azarbaijan

BACKGROUND AND OBJECTIVE: Celiac disease (CD) is a chronic enteropathy caused by hypersensitivity to gluten. Most studies have shown more prevalence of CD in the patients with diabetes mellitus type 1 (DM1). The prevalence of CD among DM1 children is unknown. The aim of this study is to survey the p...

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Autores principales:	R Ghergherehchi, M Rafeey, J Majidi, S Majidi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2010
Materias:	diabetes melliuts type 1 celiac disease Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/f5b0afb7280747288e9e64e36d868216
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spelling	oai:doaj.org-article:f5b0afb7280747288e9e64e36d8682162021-11-10T09:00:07ZPrevalence of Celiac Disease in Type 1 Diabetic Children and adolescents in East Azarbaijan1561-41072251-7170https://doaj.org/article/f5b0afb7280747288e9e64e36d8682162010-01-01T00:00:00Zhttp://jbums.org/article-1-3372-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Celiac disease (CD) is a chronic enteropathy caused by hypersensitivity to gluten. Most studies have shown more prevalence of CD in the patients with diabetes mellitus type 1 (DM1). The prevalence of CD among DM1 children is unknown. The aim of this study is to survey the prevalence of celiac disease in type 1 diabetic children in East Azarbaijan. METHODS: In a cross-sectional study, 135 children with diabetes mellitus type 1 referring to Tabriz children hospital endocrine department and clinic from 2006 to 2008 were selected. The serumic level of A-tTG-A-IgA and AEA-IgA were measured by ELISA method and serum IgA level was measured by nephelometry for screening of celiac disease. In the case that A-tTG-A either AEA was high, distal duodenal biopsy was preformed. FINDINGS: Twenty eight of 135 patients with diabetes mellitus type 1, were serologically positive for celiac. Four of 28 (14.28%) seropositive paitients were A-tTG-A positive, ten (35.71%) of them were AEA positive and fourteen (50%) were A-tTG-A and AEA positive. Confirmed celiac prevalence based on biopsy was 6.8%.CONCLUSION: Celiac disease in diabetic patients (DM1) is common. Screening of celiac disease with serologic tests in diabetic patients is necessary for the purpose of early diagnosis and prevention from severe complications of celiac disease.R Ghergherehchi,M RafeeyJ MajidiS MajidiBabol University of Medical Sciencesarticlediabetes melliutstype 1celiac diseaseMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 11, Iss 6, Pp 40-45 (2010)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	diabetes melliuts type 1 celiac disease Medicine R Medicine (General) R5-920
spellingShingle	diabetes melliuts type 1 celiac disease Medicine R Medicine (General) R5-920 R Ghergherehchi, M Rafeey J Majidi S Majidi Prevalence of Celiac Disease in Type 1 Diabetic Children and adolescents in East Azarbaijan
description	BACKGROUND AND OBJECTIVE: Celiac disease (CD) is a chronic enteropathy caused by hypersensitivity to gluten. Most studies have shown more prevalence of CD in the patients with diabetes mellitus type 1 (DM1). The prevalence of CD among DM1 children is unknown. The aim of this study is to survey the prevalence of celiac disease in type 1 diabetic children in East Azarbaijan. METHODS: In a cross-sectional study, 135 children with diabetes mellitus type 1 referring to Tabriz children hospital endocrine department and clinic from 2006 to 2008 were selected. The serumic level of A-tTG-A-IgA and AEA-IgA were measured by ELISA method and serum IgA level was measured by nephelometry for screening of celiac disease. In the case that A-tTG-A either AEA was high, distal duodenal biopsy was preformed. FINDINGS: Twenty eight of 135 patients with diabetes mellitus type 1, were serologically positive for celiac. Four of 28 (14.28%) seropositive paitients were A-tTG-A positive, ten (35.71%) of them were AEA positive and fourteen (50%) were A-tTG-A and AEA positive. Confirmed celiac prevalence based on biopsy was 6.8%.CONCLUSION: Celiac disease in diabetic patients (DM1) is common. Screening of celiac disease with serologic tests in diabetic patients is necessary for the purpose of early diagnosis and prevention from severe complications of celiac disease.
format	article
author	R Ghergherehchi, M Rafeey J Majidi S Majidi
author_facet	R Ghergherehchi, M Rafeey J Majidi S Majidi
author_sort	R Ghergherehchi,
title	Prevalence of Celiac Disease in Type 1 Diabetic Children and adolescents in East Azarbaijan
title_short	Prevalence of Celiac Disease in Type 1 Diabetic Children and adolescents in East Azarbaijan
title_full	Prevalence of Celiac Disease in Type 1 Diabetic Children and adolescents in East Azarbaijan
title_fullStr	Prevalence of Celiac Disease in Type 1 Diabetic Children and adolescents in East Azarbaijan
title_full_unstemmed	Prevalence of Celiac Disease in Type 1 Diabetic Children and adolescents in East Azarbaijan
title_sort	prevalence of celiac disease in type 1 diabetic children and adolescents in east azarbaijan
publisher	Babol University of Medical Sciences
publishDate	2010
url	https://doaj.org/article/f5b0afb7280747288e9e64e36d868216
work_keys_str_mv	AT rghergherehchi prevalenceofceliacdiseaseintype1diabeticchildrenandadolescentsineastazarbaijan AT mrafeey prevalenceofceliacdiseaseintype1diabeticchildrenandadolescentsineastazarbaijan AT jmajidi prevalenceofceliacdiseaseintype1diabeticchildrenandadolescentsineastazarbaijan AT smajidi prevalenceofceliacdiseaseintype1diabeticchildrenandadolescentsineastazarbaijan
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Prevalence of Celiac Disease in Type 1 Diabetic Children and adolescents in East Azarbaijan

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