Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis
Abstract We previously reported that synovial mast cells (MCs) from patients with rheumatoid arthritis (RA) produced TNF-α in response to immune complexes via FcγRI and FcγRIIA. However, the specific functions of synovial MCs in RA remain unclear. This study aimed to elucidate those functions. Synov...
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Auteurs principaux: | Shintaro Mishima, Jun-ichi Kashiwakura, Shota Toyoshima, Tomomi Sasaki-Sakamoto, Yutaka Sano, Kazuyoshi Nakanishi, Kenji Matsumoto, Yoshimichi Okayama |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Sujets: | |
Accès en ligne: | https://doaj.org/article/f5b5fbc6f1e848db976dde89bfbb4662 |
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