Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum

Elizabeth Egan and colleagues demonstrate that host ATP binding cassette transporter ABCB6, which encodes the Langereis blood group antigen, promotes erythrocyte invasion by the malaria parasite Plasmodium falciparum. This study suggests that asymptomatic Langereis null individuals may be better pro...

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Autores principales:	Elizabeth S. Egan, Michael P. Weekes, Usheer Kanjee, Jale Manzo, Ashwin Srinivasan, Christine Lomas-Francis, Connie Westhoff, Junko Takahashi, Mitsunobu Tanaka, Seishi Watanabe, Carlo Brugnara, Steven P. Gygi, Yoshihiko Tani, Manoj T. Duraisingh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/f5b78d5ccae641ef9b5e33130b201eaa
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spelling	oai:doaj.org-article:f5b78d5ccae641ef9b5e33130b201eaa2021-12-02T16:19:52ZErythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum10.1038/s42003-018-0046-22399-3642https://doaj.org/article/f5b78d5ccae641ef9b5e33130b201eaa2018-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-018-0046-2https://doaj.org/toc/2399-3642Elizabeth Egan and colleagues demonstrate that host ATP binding cassette transporter ABCB6, which encodes the Langereis blood group antigen, promotes erythrocyte invasion by the malaria parasite Plasmodium falciparum. This study suggests that asymptomatic Langereis null individuals may be better protected from malaria.Elizabeth S. EganMichael P. WeekesUsheer KanjeeJale ManzoAshwin SrinivasanChristine Lomas-FrancisConnie WesthoffJunko TakahashiMitsunobu TanakaSeishi WatanabeCarlo BrugnaraSteven P. GygiYoshihiko TaniManoj T. DuraisinghNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 1, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Elizabeth S. Egan Michael P. Weekes Usheer Kanjee Jale Manzo Ashwin Srinivasan Christine Lomas-Francis Connie Westhoff Junko Takahashi Mitsunobu Tanaka Seishi Watanabe Carlo Brugnara Steven P. Gygi Yoshihiko Tani Manoj T. Duraisingh Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum
description	Elizabeth Egan and colleagues demonstrate that host ATP binding cassette transporter ABCB6, which encodes the Langereis blood group antigen, promotes erythrocyte invasion by the malaria parasite Plasmodium falciparum. This study suggests that asymptomatic Langereis null individuals may be better protected from malaria.
format	article
author	Elizabeth S. Egan Michael P. Weekes Usheer Kanjee Jale Manzo Ashwin Srinivasan Christine Lomas-Francis Connie Westhoff Junko Takahashi Mitsunobu Tanaka Seishi Watanabe Carlo Brugnara Steven P. Gygi Yoshihiko Tani Manoj T. Duraisingh
author_facet	Elizabeth S. Egan Michael P. Weekes Usheer Kanjee Jale Manzo Ashwin Srinivasan Christine Lomas-Francis Connie Westhoff Junko Takahashi Mitsunobu Tanaka Seishi Watanabe Carlo Brugnara Steven P. Gygi Yoshihiko Tani Manoj T. Duraisingh
author_sort	Elizabeth S. Egan
title	Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum
title_short	Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum
title_full	Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum
title_fullStr	Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum
title_full_unstemmed	Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum
title_sort	erythrocytes lacking the langereis blood group protein abcb6 are resistant to the malaria parasite plasmodium falciparum
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f5b78d5ccae641ef9b5e33130b201eaa
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Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum

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