Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum

Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum

Elizabeth Egan and colleagues demonstrate that host ATP binding cassette transporter ABCB6, which encodes the Langereis blood group antigen, promotes erythrocyte invasion by the malaria parasite Plasmodium falciparum. This study suggests that asymptomatic Langereis null individuals may be better pro...

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Bibliographic Details
Main Authors: Elizabeth S. Egan, Michael P. Weekes, Usheer Kanjee, Jale Manzo, Ashwin Srinivasan, Christine Lomas-Francis, Connie Westhoff, Junko Takahashi, Mitsunobu Tanaka, Seishi Watanabe, Carlo Brugnara, Steven P. Gygi, Yoshihiko Tani, Manoj T. Duraisingh
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/f5b78d5ccae641ef9b5e33130b201eaa
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