DIP1 modulates stem cell homeostasis in Drosophila through regulation of sisR-1
Stable intronic sequence RNAs (sisRNAs) are by-products of splicing from introns with roles in embryonic development in Drosophila. Here, the authors show that the RNA binding protein DIP1 regulates sisRNAs in Drosophila, which is necessary for germline stem cell homeostasis.
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Nature Portfolio
2017
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oai:doaj.org-article:f5b9004081984bb9a7ce59a01c81c5332021-12-02T14:42:21ZDIP1 modulates stem cell homeostasis in Drosophila through regulation of sisR-110.1038/s41467-017-00684-42041-1723https://doaj.org/article/f5b9004081984bb9a7ce59a01c81c5332017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00684-4https://doaj.org/toc/2041-1723Stable intronic sequence RNAs (sisRNAs) are by-products of splicing from introns with roles in embryonic development in Drosophila. Here, the authors show that the RNA binding protein DIP1 regulates sisRNAs in Drosophila, which is necessary for germline stem cell homeostasis.Jing Ting WongFarzanah AkhbarAmanda Yunn Ee NgMandy Li-Ian TayGladys Jing En LoiJun Wei PekNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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Science Q Jing Ting Wong Farzanah Akhbar Amanda Yunn Ee Ng Mandy Li-Ian Tay Gladys Jing En Loi Jun Wei Pek DIP1 modulates stem cell homeostasis in Drosophila through regulation of sisR-1 |
description |
Stable intronic sequence RNAs (sisRNAs) are by-products of splicing from introns with roles in embryonic development in Drosophila. Here, the authors show that the RNA binding protein DIP1 regulates sisRNAs in Drosophila, which is necessary for germline stem cell homeostasis. |
format |
article |
author |
Jing Ting Wong Farzanah Akhbar Amanda Yunn Ee Ng Mandy Li-Ian Tay Gladys Jing En Loi Jun Wei Pek |
author_facet |
Jing Ting Wong Farzanah Akhbar Amanda Yunn Ee Ng Mandy Li-Ian Tay Gladys Jing En Loi Jun Wei Pek |
author_sort |
Jing Ting Wong |
title |
DIP1 modulates stem cell homeostasis in Drosophila through regulation of sisR-1 |
title_short |
DIP1 modulates stem cell homeostasis in Drosophila through regulation of sisR-1 |
title_full |
DIP1 modulates stem cell homeostasis in Drosophila through regulation of sisR-1 |
title_fullStr |
DIP1 modulates stem cell homeostasis in Drosophila through regulation of sisR-1 |
title_full_unstemmed |
DIP1 modulates stem cell homeostasis in Drosophila through regulation of sisR-1 |
title_sort |
dip1 modulates stem cell homeostasis in drosophila through regulation of sisr-1 |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/f5b9004081984bb9a7ce59a01c81c533 |
work_keys_str_mv |
AT jingtingwong dip1modulatesstemcellhomeostasisindrosophilathroughregulationofsisr1 AT farzanahakhbar dip1modulatesstemcellhomeostasisindrosophilathroughregulationofsisr1 AT amandayunneeng dip1modulatesstemcellhomeostasisindrosophilathroughregulationofsisr1 AT mandyliiantay dip1modulatesstemcellhomeostasisindrosophilathroughregulationofsisr1 AT gladysjingenloi dip1modulatesstemcellhomeostasisindrosophilathroughregulationofsisr1 AT junweipek dip1modulatesstemcellhomeostasisindrosophilathroughregulationofsisr1 |
_version_ |
1718389726766956544 |