Back to the Future: Studying Cholera Pathogenesis Using Infant Rabbits

ABSTRACT Cholera is a severe diarrheal disease, caused by Vibrio cholerae, for which there has been no reproducible, nonsurgical animal model. Here, we report that orogastric inoculation of V. cholerae into 3-day-old rabbits pretreated with cimetidine led to lethal, watery diarrhea in virtually all...

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Bibliographic Details
Main Authors: Jennifer M. Ritchie, Haopeng Rui, Roderick T. Bronson, Matthew K. Waldor
Format: article
Language:EN
Published: American Society for Microbiology 2010
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Online Access:https://doaj.org/article/f5bcf7bf0d90495d87dde76f70e0ed93
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