Molecular transport through large-diameter DNA nanopores

Artificial DNA membrane channels are promising molecular devices for biotechnology but suffer from low affinity for lipid bilayers. Here, the authors report a large DNA nanopore that spontaneously inserts into a flat lipid membrane, driven by engineered hydrophobic or streptavidin-biotin interaction...

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Autores principales:	Swati Krishnan, Daniela Ziegler, Vera Arnaut, Thomas G. Martin, Korbinian Kapsner, Katharina Henneberg, Andreas R. Bausch, Hendrik Dietz, Friedrich C. Simmel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f5c4ba23f6fd4684991fbd8b41495255
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spelling	oai:doaj.org-article:f5c4ba23f6fd4684991fbd8b414952552021-12-02T15:35:25ZMolecular transport through large-diameter DNA nanopores10.1038/ncomms127872041-1723https://doaj.org/article/f5c4ba23f6fd4684991fbd8b414952552016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12787https://doaj.org/toc/2041-1723Artificial DNA membrane channels are promising molecular devices for biotechnology but suffer from low affinity for lipid bilayers. Here, the authors report a large DNA nanopore that spontaneously inserts into a flat lipid membrane, driven by engineered hydrophobic or streptavidin-biotin interactions.Swati KrishnanDaniela ZieglerVera ArnautThomas G. MartinKorbinian KapsnerKatharina HennebergAndreas R. BauschHendrik DietzFriedrich C. SimmelNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Swati Krishnan Daniela Ziegler Vera Arnaut Thomas G. Martin Korbinian Kapsner Katharina Henneberg Andreas R. Bausch Hendrik Dietz Friedrich C. Simmel Molecular transport through large-diameter DNA nanopores
description	Artificial DNA membrane channels are promising molecular devices for biotechnology but suffer from low affinity for lipid bilayers. Here, the authors report a large DNA nanopore that spontaneously inserts into a flat lipid membrane, driven by engineered hydrophobic or streptavidin-biotin interactions.
format	article
author	Swati Krishnan Daniela Ziegler Vera Arnaut Thomas G. Martin Korbinian Kapsner Katharina Henneberg Andreas R. Bausch Hendrik Dietz Friedrich C. Simmel
author_facet	Swati Krishnan Daniela Ziegler Vera Arnaut Thomas G. Martin Korbinian Kapsner Katharina Henneberg Andreas R. Bausch Hendrik Dietz Friedrich C. Simmel
author_sort	Swati Krishnan
title	Molecular transport through large-diameter DNA nanopores
title_short	Molecular transport through large-diameter DNA nanopores
title_full	Molecular transport through large-diameter DNA nanopores
title_fullStr	Molecular transport through large-diameter DNA nanopores
title_full_unstemmed	Molecular transport through large-diameter DNA nanopores
title_sort	molecular transport through large-diameter dna nanopores
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f5c4ba23f6fd4684991fbd8b41495255
work_keys_str_mv	AT swatikrishnan moleculartransportthroughlargediameterdnananopores AT danielaziegler moleculartransportthroughlargediameterdnananopores AT veraarnaut moleculartransportthroughlargediameterdnananopores AT thomasgmartin moleculartransportthroughlargediameterdnananopores AT korbiniankapsner moleculartransportthroughlargediameterdnananopores AT katharinahenneberg moleculartransportthroughlargediameterdnananopores AT andreasrbausch moleculartransportthroughlargediameterdnananopores AT hendrikdietz moleculartransportthroughlargediameterdnananopores AT friedrichcsimmel moleculartransportthroughlargediameterdnananopores
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Molecular transport through large-diameter DNA nanopores

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