Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis
T cells express specific T cell receptors (TCR) to recognise antigens and initiate adaptive immune responses. Here the authors show, in a mouse model of autoimmune encephalomyelitis, that memory-like CD4 T cells expressing unrelated TCR can also infiltrate the spinal cord and contribute to autoimmun...
Enregistré dans:
Auteurs principaux: | Hong-Gyun Lee, Jae-Ung Lee, Do-Hyun Kim, Sangho Lim, Insoo Kang, Je-Min Choi |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f5ca5d0dc6154b18a6af33804ceb6a15 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis.
par: Helena S Domingues, et autres
Publié: (2010) -
CXCR3 enables recruitment and site-specific bystander activation of memory CD8+ T cells
par: Nicholas J. Maurice, et autres
Publié: (2019) -
IL-23p19 and CD5 antigen-like form a possible novel heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development
par: Hideaki Hasegawa, et autres
Publié: (2021) -
Hormones in experimental autoimmune encephalomyelitis (EAE) animal models
par: Ghareghani Majid, et autres
Publié: (2021) -
Translational utility of experimental autoimmune encephalomyelitis: recent developments
par: Guerreiro-Cacais AO, et autres
Publié: (2015)