Rescue of the 1947 Zika Virus Prototype Strain with a Cytomegalovirus Promoter-Driven cDNA Clone

ABSTRACT The recent Zika virus (ZIKV) outbreak has been linked to severe pathogenesis. Here, we report the construction of a plasmid carrying a cytomegalovirus (CMV) promoter-expressed prototype 1947 Uganda MR766 ZIKV cDNA that can initiate infection following direct plasmid DNA transfection of mamm...

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Autores principales: Megan C. Schwarz, Marion Sourisseau, Michael M. Espino, Essanna S. Gray, Matthew T. Chambers, Domenico Tortorella, Matthew J. Evans
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://doaj.org/article/f5cd5e0f9e134feaa577a3c6956858fc
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