Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores

Protein nanopores are emerging as sensors for a variety of biomolecules. Here the authors develop a nanopore based on the bacterial toxin ClyA, in conjunction with binding proteins for glucose and asparagine, to detect these biomolecules simultaneously from a variety of unprocessed, diluted body flu...

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Bibliographic Details
Main Authors: Nicole Stéphanie Galenkamp, Misha Soskine, Jos Hermans, Carsten Wloka, Giovanni Maglia
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/f5d06fa761e34c8ab22f09254e397e18
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Summary:Protein nanopores are emerging as sensors for a variety of biomolecules. Here the authors develop a nanopore based on the bacterial toxin ClyA, in conjunction with binding proteins for glucose and asparagine, to detect these biomolecules simultaneously from a variety of unprocessed, diluted body fluids.