Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores

Protein nanopores are emerging as sensors for a variety of biomolecules. Here the authors develop a nanopore based on the bacterial toxin ClyA, in conjunction with binding proteins for glucose and asparagine, to detect these biomolecules simultaneously from a variety of unprocessed, diluted body flu...

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Autores principales: Nicole Stéphanie Galenkamp, Misha Soskine, Jos Hermans, Carsten Wloka, Giovanni Maglia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f5d06fa761e34c8ab22f09254e397e18
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spelling oai:doaj.org-article:f5d06fa761e34c8ab22f09254e397e182021-12-02T15:34:28ZDirect electrical quantification of glucose and asparagine from bodily fluids using nanopores10.1038/s41467-018-06534-12041-1723https://doaj.org/article/f5d06fa761e34c8ab22f09254e397e182018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06534-1https://doaj.org/toc/2041-1723Protein nanopores are emerging as sensors for a variety of biomolecules. Here the authors develop a nanopore based on the bacterial toxin ClyA, in conjunction with binding proteins for glucose and asparagine, to detect these biomolecules simultaneously from a variety of unprocessed, diluted body fluids.Nicole Stéphanie GalenkampMisha SoskineJos HermansCarsten WlokaGiovanni MagliaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nicole Stéphanie Galenkamp
Misha Soskine
Jos Hermans
Carsten Wloka
Giovanni Maglia
Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores
description Protein nanopores are emerging as sensors for a variety of biomolecules. Here the authors develop a nanopore based on the bacterial toxin ClyA, in conjunction with binding proteins for glucose and asparagine, to detect these biomolecules simultaneously from a variety of unprocessed, diluted body fluids.
format article
author Nicole Stéphanie Galenkamp
Misha Soskine
Jos Hermans
Carsten Wloka
Giovanni Maglia
author_facet Nicole Stéphanie Galenkamp
Misha Soskine
Jos Hermans
Carsten Wloka
Giovanni Maglia
author_sort Nicole Stéphanie Galenkamp
title Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores
title_short Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores
title_full Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores
title_fullStr Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores
title_full_unstemmed Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores
title_sort direct electrical quantification of glucose and asparagine from bodily fluids using nanopores
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f5d06fa761e34c8ab22f09254e397e18
work_keys_str_mv AT nicolestephaniegalenkamp directelectricalquantificationofglucoseandasparaginefrombodilyfluidsusingnanopores
AT mishasoskine directelectricalquantificationofglucoseandasparaginefrombodilyfluidsusingnanopores
AT joshermans directelectricalquantificationofglucoseandasparaginefrombodilyfluidsusingnanopores
AT carstenwloka directelectricalquantificationofglucoseandasparaginefrombodilyfluidsusingnanopores
AT giovannimaglia directelectricalquantificationofglucoseandasparaginefrombodilyfluidsusingnanopores
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