Changes in cortical gene expression in the muscarinic M1 receptor knockout mouse: potential relevance to schizophrenia, Alzheimer’s disease and cognition
Abstract Postmortem and neuroimaging studies show low levels of cortical muscarinic M1 receptors (CHRM1) in patients with schizophrenia which is significant because CHRM signalling has been shown to change levels of gene expression and cortical gene expression is altered in schizophrenia. We decided...
Guardado en:
Autores principales: | Brian Dean, Elizabeth Scarr |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f5d1a6cc2fbf49c198d455a4481819e1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Cognitive impairment in schizophrenia: relationships with cortical thickness in fronto-temporal regions, and dissociability from symptom severity
por: Erkan Alkan, et al.
Publicado: (2021) -
Avolition as the core negative symptom in schizophrenia: relevance to pharmacological treatment development
por: Gregory P. Strauss, et al.
Publicado: (2021) -
No association between cortical dopamine D2 receptor availability and cognition in antipsychotic-naive first-episode psychosis
por: Maria Lee, et al.
Publicado: (2021) -
The effect of sex on social cognition and functioning in schizophrenia
por: Marta Ferrer-Quintero, et al.
Publicado: (2021) -
Isoform specific differences in phospholipase C beta 1 expression in the prefrontal cortex in schizophrenia and suicide
por: M. Udawela, et al.
Publicado: (2017)