LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment
Mechanism of lymph node (LN) metastasis induced by tumor associated macrophages (TAMs) remains unclear. Here they demonstrate that a long noncoding RNA LNMAT1 promotes LN metastasis of bladder cancer via recruitment of TAMs through epigenetic regulation of CCL2 expression.
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Auteurs principaux: | Changhao Chen, Wang He, Jian Huang, Bo Wang, Hui Li, Qingqing Cai, Feng Su, Junming Bi, Hongwei Liu, Bin Zhang, Ning Jiang, Guangzheng Zhong, Yue Zhao, Wen Dong, Tianxin Lin |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Sujets: | |
Accès en ligne: | https://doaj.org/article/f5d2240101054e48aeea263d84e7d95f |
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