Validation of AD8-Philippines (AD8-P): A Brief Informant-Based Questionnaire for Dementia Screening in the Philippines

Aim. This study was aimed at validating the Filipino version of AD8 (AD8-P). Methods. Community-dwelling Filipino older persons aged ≥60 years, together with their informants, participated in this study. Psychologists independently interviewed the informants with AD8-P and administered the Filipino-...

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Autores principales:	Jacqueline C. Dominguez, Ma. Fe P. de Guzman, Ma. Lourdes C. Joson, Krizelle Fowler, Boots P. Natividad, Precy S. Cruz, Jose Leo Jiloca, Primitivo B. Mactal, Jayvee Dyne Dominguez, Jeffrey Domingo, Jhozel Kim Dominguez-Awao, Macario Reandelar, Jem R. Javier, ThienKieuThi Phung, John C. Morris, James E. Galvin
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/f5d230c07d5e4cd182b2809016a286fc
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spelling	oai:doaj.org-article:f5d230c07d5e4cd182b2809016a286fc2021-11-08T02:37:24ZValidation of AD8-Philippines (AD8-P): A Brief Informant-Based Questionnaire for Dementia Screening in the Philippines2090-025210.1155/2021/7750235https://doaj.org/article/f5d230c07d5e4cd182b2809016a286fc2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/7750235https://doaj.org/toc/2090-0252Aim. This study was aimed at validating the Filipino version of AD8 (AD8-P). Methods. Community-dwelling Filipino older persons aged ≥60 years, together with their informants, participated in this study. Psychologists independently interviewed the informants with AD8-P and administered the Filipino-validated Mini-Mental State Examination (MMSE-P) and Montreal Cognitive Assessment (MoCA-P) to the older persons. Neurologists and geriatrician conducted physical and neurological examination and Clinical Dementia Rating™ (CDR™) to determine cognitive diagnosis and were blinded with the results of AD8-P. Dementia was diagnosed based on DSM-IV-TR criteria. AD8-P discriminatory ability to screen for dementia was evaluated according to DSM-IV-TR diagnostic criteria for dementia. Results. A total of 366 community-dwelling Filipino older persons aged ≥60 years, 213 with normal cognition and 153 with dementia, and their informants were included in this study. Majority (90%) were at the mildest stage of dementia. Area under the receiver-operating-characteristic curve (AUROC) for AD8-P was 0.94 (95% CI 0.92 to 0.96), demonstrating excellent overall predictive power to screen for dementia. The optimal AD8-P cut-off score with best balance sensitivity (91.5%) and specificity (77.9%) was ≥3. Conclusion. AD8-P demonstrated good psychometric properties to screen for dementia, even at the earliest stage of cognitive decline.Jacqueline C. DominguezMa. Fe P. de GuzmanMa. Lourdes C. JosonKrizelle FowlerBoots P. NatividadPrecy S. CruzJose Leo JilocaPrimitivo B. MactalJayvee Dyne DominguezJeffrey DomingoJhozel Kim Dominguez-AwaoMacario ReandelarJem R. JavierThienKieuThi PhungJohn C. MorrisJames E. GalvinHindawi LimitedarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571GeriatricsRC952-954.6ENInternational Journal of Alzheimer's Disease, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Geriatrics RC952-954.6
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Geriatrics RC952-954.6 Jacqueline C. Dominguez Ma. Fe P. de Guzman Ma. Lourdes C. Joson Krizelle Fowler Boots P. Natividad Precy S. Cruz Jose Leo Jiloca Primitivo B. Mactal Jayvee Dyne Dominguez Jeffrey Domingo Jhozel Kim Dominguez-Awao Macario Reandelar Jem R. Javier ThienKieuThi Phung John C. Morris James E. Galvin Validation of AD8-Philippines (AD8-P): A Brief Informant-Based Questionnaire for Dementia Screening in the Philippines
description	Aim. This study was aimed at validating the Filipino version of AD8 (AD8-P). Methods. Community-dwelling Filipino older persons aged ≥60 years, together with their informants, participated in this study. Psychologists independently interviewed the informants with AD8-P and administered the Filipino-validated Mini-Mental State Examination (MMSE-P) and Montreal Cognitive Assessment (MoCA-P) to the older persons. Neurologists and geriatrician conducted physical and neurological examination and Clinical Dementia Rating™ (CDR™) to determine cognitive diagnosis and were blinded with the results of AD8-P. Dementia was diagnosed based on DSM-IV-TR criteria. AD8-P discriminatory ability to screen for dementia was evaluated according to DSM-IV-TR diagnostic criteria for dementia. Results. A total of 366 community-dwelling Filipino older persons aged ≥60 years, 213 with normal cognition and 153 with dementia, and their informants were included in this study. Majority (90%) were at the mildest stage of dementia. Area under the receiver-operating-characteristic curve (AUROC) for AD8-P was 0.94 (95% CI 0.92 to 0.96), demonstrating excellent overall predictive power to screen for dementia. The optimal AD8-P cut-off score with best balance sensitivity (91.5%) and specificity (77.9%) was ≥3. Conclusion. AD8-P demonstrated good psychometric properties to screen for dementia, even at the earliest stage of cognitive decline.
format	article
author	Jacqueline C. Dominguez Ma. Fe P. de Guzman Ma. Lourdes C. Joson Krizelle Fowler Boots P. Natividad Precy S. Cruz Jose Leo Jiloca Primitivo B. Mactal Jayvee Dyne Dominguez Jeffrey Domingo Jhozel Kim Dominguez-Awao Macario Reandelar Jem R. Javier ThienKieuThi Phung John C. Morris James E. Galvin
author_facet	Jacqueline C. Dominguez Ma. Fe P. de Guzman Ma. Lourdes C. Joson Krizelle Fowler Boots P. Natividad Precy S. Cruz Jose Leo Jiloca Primitivo B. Mactal Jayvee Dyne Dominguez Jeffrey Domingo Jhozel Kim Dominguez-Awao Macario Reandelar Jem R. Javier ThienKieuThi Phung John C. Morris James E. Galvin
author_sort	Jacqueline C. Dominguez
title	Validation of AD8-Philippines (AD8-P): A Brief Informant-Based Questionnaire for Dementia Screening in the Philippines
title_short	Validation of AD8-Philippines (AD8-P): A Brief Informant-Based Questionnaire for Dementia Screening in the Philippines
title_full	Validation of AD8-Philippines (AD8-P): A Brief Informant-Based Questionnaire for Dementia Screening in the Philippines
title_fullStr	Validation of AD8-Philippines (AD8-P): A Brief Informant-Based Questionnaire for Dementia Screening in the Philippines
title_full_unstemmed	Validation of AD8-Philippines (AD8-P): A Brief Informant-Based Questionnaire for Dementia Screening in the Philippines
title_sort	validation of ad8-philippines (ad8-p): a brief informant-based questionnaire for dementia screening in the philippines
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/f5d230c07d5e4cd182b2809016a286fc
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Validation of AD8-Philippines (AD8-P): A Brief Informant-Based Questionnaire for Dementia Screening in the Philippines

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