Pancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation
Glycoprotein-2 (GP-2) can protect the intestinal epithelial barrier from bacteria and is associated with protection against Crohn’s disease. Here, the authors show pancreatic GP-2 is the source of the intestine’s luminal GP-2 that binds bacteria and prevents them from attaching to the epithelium, al...
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Autores principales: | Yosuke Kurashima, Takaaki Kigoshi, Sayuri Murasaki, Fujimi Arai, Kaoru Shimada, Natsumi Seki, Yun-Gi Kim, Koji Hase, Hiroshi Ohno, Kazuya Kawano, Hiroshi Ashida, Toshihiko Suzuki, Masako Morimoto, Yukari Saito, Ai Sasou, Yuki Goda, Yoshikazu Yuki, Yutaka Inagaki, Hideki Iijima, Wataru Suda, Masahira Hattori, Hiroshi Kiyono |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/f5da787852fa46ccab231d2284892574 |
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