Somatotype and Its Impact on Asymptomatic Target Organ Damage in the Elderly Chinese: The Northern Shanghai Study
Jing Xiong,1,* Yunyun Qian,1,* Shikai Yu,1 HongWei Ji,1 Jiadela Teliewubai,1 Chen Chi,1 YuYan Lu,1 YiWu Zhou,1 XiMin Fan,1 Jue Li,2 Jacques Blacher,3 Yi Zhang,1 YaWei Xu1 1Department of Cardiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People&...
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| Autores principales: | , , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
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Dove Medical Press
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/f5dc94d05c8d44ff8677d158a678ae48 |
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| Sumario: | Jing Xiong,1,* Yunyun Qian,1,* Shikai Yu,1 HongWei Ji,1 Jiadela Teliewubai,1 Chen Chi,1 YuYan Lu,1 YiWu Zhou,1 XiMin Fan,1 Jue Li,2 Jacques Blacher,3 Yi Zhang,1 YaWei Xu1 1Department of Cardiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 2The Research Institute of Clinical Epidemiology, Tongji University School of Medicine, Shanghai, People’s Republic of China; 3Paris Descartes University, AP-HP, Diagnosis and Therapeutic Center, Hôtel-Dieu, Paris, France*These authors contributed equally to this workCorrespondence: Yi Zhang; Yawei XuDepartment of Cardiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, 301 Yanchang Road, Shanghai, 200072, ChinaTel +86-21-66308182Fax +86-21-66301051Email yizshcn@gmail.com; xuyawei@tongji.edu.cnObjective: To investigate the relationship between asymptomatic target organ damage (TOD) and different somatotypes in a population of elderly from Chinese community-dwelling.Methods: A total of 2098 Chinese senior residents from northern Shanghai older than 65 years were recruited in the research. The following somatotype parameters were recorded and analyzed: body mass index, waist circumference, hip circumference, and waist-hip ratio were recorded and calculated. Asymptomatic TOD, including urine albumin/creatinine ratio, estimated glomerular filtration rate (eGFR), intima-media thickness (IMT), left ventricular mass index (LVMI), left ventricular diastolic function, and carotid-femoral pulse wave velocity (PWV) was recorded using the MyLab30 Gold CV system and SphygmoCor.Results: Of all 2098 residents, 817 (38.9%) were overweight and 289 (13.8%) were obese. All somatotype measures were significantly correlated with TOD parameters (p< 0.05). After adjustment for age and male gender, in total population, LVMI (p< 0.001), cardiac diastolic function (E/Ea, p< 0.001), PWV (p< 0.001), eGFR (p=0.03), and urine albumin/creatinine ratio (p< 0.001) changed gradually and significantly correlated with increasing BMI values. Obesity and overweight were independently related to the incidence of LVH, LVDD, artery stiffness, carotid arterial plaque, and microalbuminuria.Conclusion: The incidence of asymptomatic TOD was significantly correlated with overweight and obesity, especially in women, whereas the underweight may favor in the prevention of TOD.Keywords: Chinese elderly cardiovascular risk |
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