Emerging roles for antiangiogenesis factors in management of ocular disease

Muhammad Usman Saeed,1 Evangelia Gkaragkani,1 Kashif Ali2 1The Sutton Eye Unit, Epsom and St Helier&rsquo;s University Hospitals NHS Trust, London, UK; 2Department of Ophthalmology, Countess of Chester Hospital NHS Foundation Trust, Chester, UK Abstract: The first antivascular endothelial gr...

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Autores principales:	Saeed MU, Gkaragkani E, Ali K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f5f0f1ce76874301a35eb258ce4eff45
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spelling	oai:doaj.org-article:f5f0f1ce76874301a35eb258ce4eff452021-12-02T03:55:15ZEmerging roles for antiangiogenesis factors in management of ocular disease1177-54671177-5483https://doaj.org/article/f5f0f1ce76874301a35eb258ce4eff452013-03-01T00:00:00Zhttp://www.dovepress.com/emerging-roles-for-antiangiogenesis-factors-in-management-of-ocular-di-a12456https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Muhammad Usman Saeed,1 Evangelia Gkaragkani,1 Kashif Ali2 1The Sutton Eye Unit, Epsom and St Helier&rsquo;s University Hospitals NHS Trust, London, UK; 2Department of Ophthalmology, Countess of Chester Hospital NHS Foundation Trust, Chester, UK Abstract: The first antivascular endothelial growth factor (anti-VEGF) was developed as an anticancer drug for colonic carcinomas. Since then, anti-VEGFs have developed in scope and indications. They have revolutionized the treatment of exudative macular degeneration and have had a major impact on treatment of several other conditions. This has resulted in an increased number of patients seeking treatment with new treatment options and has had a considerable financial impact on health care resources. Anti-VEGFs have been used in the treatment of all age groups of the population ranging from infants where it is used for treatment of retinopathy of prematurity to the elderly where it is used in exudative macular eegeneration. Keywords: ranibizumab, bevacizumab, pegaptanib, retina, aflibercept, indicationsSaeed MUGkaragkani EAli KDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 533-543 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Saeed MU Gkaragkani E Ali K Emerging roles for antiangiogenesis factors in management of ocular disease
description	Muhammad Usman Saeed,1 Evangelia Gkaragkani,1 Kashif Ali2 1The Sutton Eye Unit, Epsom and St Helier&rsquo;s University Hospitals NHS Trust, London, UK; 2Department of Ophthalmology, Countess of Chester Hospital NHS Foundation Trust, Chester, UK Abstract: The first antivascular endothelial growth factor (anti-VEGF) was developed as an anticancer drug for colonic carcinomas. Since then, anti-VEGFs have developed in scope and indications. They have revolutionized the treatment of exudative macular degeneration and have had a major impact on treatment of several other conditions. This has resulted in an increased number of patients seeking treatment with new treatment options and has had a considerable financial impact on health care resources. Anti-VEGFs have been used in the treatment of all age groups of the population ranging from infants where it is used for treatment of retinopathy of prematurity to the elderly where it is used in exudative macular eegeneration. Keywords: ranibizumab, bevacizumab, pegaptanib, retina, aflibercept, indications
format	article
author	Saeed MU Gkaragkani E Ali K
author_facet	Saeed MU Gkaragkani E Ali K
author_sort	Saeed MU
title	Emerging roles for antiangiogenesis factors in management of ocular disease
title_short	Emerging roles for antiangiogenesis factors in management of ocular disease
title_full	Emerging roles for antiangiogenesis factors in management of ocular disease
title_fullStr	Emerging roles for antiangiogenesis factors in management of ocular disease
title_full_unstemmed	Emerging roles for antiangiogenesis factors in management of ocular disease
title_sort	emerging roles for antiangiogenesis factors in management of ocular disease
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/f5f0f1ce76874301a35eb258ce4eff45
work_keys_str_mv	AT saeedmu emergingrolesforantiangiogenesisfactorsinmanagementofoculardisease AT gkaragkanie emergingrolesforantiangiogenesisfactorsinmanagementofoculardisease AT alik emergingrolesforantiangiogenesisfactorsinmanagementofoculardisease
_version_	1718401588822802432

Emerging roles for antiangiogenesis factors in management of ocular disease

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