Osteopenia and osteoporosis in people living with HIV: multiprofessional approach

Ana Lucia Lei Munhoz Lima, Priscila Rosalba D de Oliveira, Perola Grimberg Plapler, Flora Maria D Andrea Marcolino, Eduardo de Souza Meirelles, André Sugawara, Riccardo Gomes Gobbi, Alexandre Leme Godoy dos Santos , Gilberto Luis CamanhoInstitute of Orthopedics and Traumatology, Hospi...

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Autores principales: Lima AL, Oliveira PR, Plapler PG, Marcolino FM, Meirelles ES, Sugawara A, Gobbi RG, Godoy-Santos AL, Camanho GL
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Publicado: Dove Medical Press 2011
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Acceso en línea:https://doaj.org/article/f5f865ef151a466f8e957e706f3493f5
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spelling oai:doaj.org-article:f5f865ef151a466f8e957e706f3493f52021-12-02T00:23:46ZOsteopenia and osteoporosis in people living with HIV: multiprofessional approach1179-1373https://doaj.org/article/f5f865ef151a466f8e957e706f3493f52011-12-01T00:00:00Zhttp://www.dovepress.com/osteopenia-and-osteoporosis-in-people-living-with-hiv-multiprofessiona-a8826https://doaj.org/toc/1179-1373Ana Lucia Lei Munhoz Lima, Priscila Rosalba D de Oliveira, Perola Grimberg Plapler, Flora Maria D Andrea Marcolino, Eduardo de Souza Meirelles, André Sugawara, Riccardo Gomes Gobbi, Alexandre Leme Godoy dos Santos , Gilberto Luis CamanhoInstitute of Orthopedics and Traumatology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, BrazilAbstract: Increasing bone mineralization abnormalities observed among people living with HIV (PLWHIV) result from various factors relating to the host, the virus, and the antiretrovirals used. Today, HIV infection is considered to be a risk factor for bone mineralization disorders. The test most recommended for diagnosing osteoporosis is measurement of bone mineral density by means of dual energy X-ray absorptiometry at two sites. Osteoporosis treatment has the aims of bone mass improvement and fracture control. A combination of calcium and vitamin D supplementation may reduce the risk of fractures. Antiresorptive drugs act by blocking osteoclastic activity and reducing bone remodeling. On the other hand, bone-forming drugs stimulate osteoblastogenesis, thereby stimulating the formation of bone matrix. Mixed-action medications are those that are capable of both stimulating bone formation and inhibiting reabsorption. Antiresorptive drugs form the group of medications with the greatest quantity of scientific evidence confirming their efficacy in osteoporosis treatment. Physical activity is a health promotion strategy for the general population, but only preliminary data on its real value and benefit among PLWHIV are available, especially in relation to osteoporosis.Keywords: osteoporosis, HIV/AIDS, diagnosis, treatment, exerciseLima ALOliveira PRPlapler PGMarcolino FMMeirelles ESSugawara AGobbi RGGodoy-Santos ALCamanho GLDove Medical PressarticleImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol 2011, Iss default, Pp 117-124 (2011)
institution DOAJ
collection DOAJ
language EN
topic Immunologic diseases. Allergy
RC581-607
spellingShingle Immunologic diseases. Allergy
RC581-607
Lima AL
Oliveira PR
Plapler PG
Marcolino FM
Meirelles ES
Sugawara A
Gobbi RG
Godoy-Santos AL
Camanho GL
Osteopenia and osteoporosis in people living with HIV: multiprofessional approach
description Ana Lucia Lei Munhoz Lima, Priscila Rosalba D de Oliveira, Perola Grimberg Plapler, Flora Maria D Andrea Marcolino, Eduardo de Souza Meirelles, André Sugawara, Riccardo Gomes Gobbi, Alexandre Leme Godoy dos Santos , Gilberto Luis CamanhoInstitute of Orthopedics and Traumatology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, BrazilAbstract: Increasing bone mineralization abnormalities observed among people living with HIV (PLWHIV) result from various factors relating to the host, the virus, and the antiretrovirals used. Today, HIV infection is considered to be a risk factor for bone mineralization disorders. The test most recommended for diagnosing osteoporosis is measurement of bone mineral density by means of dual energy X-ray absorptiometry at two sites. Osteoporosis treatment has the aims of bone mass improvement and fracture control. A combination of calcium and vitamin D supplementation may reduce the risk of fractures. Antiresorptive drugs act by blocking osteoclastic activity and reducing bone remodeling. On the other hand, bone-forming drugs stimulate osteoblastogenesis, thereby stimulating the formation of bone matrix. Mixed-action medications are those that are capable of both stimulating bone formation and inhibiting reabsorption. Antiresorptive drugs form the group of medications with the greatest quantity of scientific evidence confirming their efficacy in osteoporosis treatment. Physical activity is a health promotion strategy for the general population, but only preliminary data on its real value and benefit among PLWHIV are available, especially in relation to osteoporosis.Keywords: osteoporosis, HIV/AIDS, diagnosis, treatment, exercise
format article
author Lima AL
Oliveira PR
Plapler PG
Marcolino FM
Meirelles ES
Sugawara A
Gobbi RG
Godoy-Santos AL
Camanho GL
author_facet Lima AL
Oliveira PR
Plapler PG
Marcolino FM
Meirelles ES
Sugawara A
Gobbi RG
Godoy-Santos AL
Camanho GL
author_sort Lima AL
title Osteopenia and osteoporosis in people living with HIV: multiprofessional approach
title_short Osteopenia and osteoporosis in people living with HIV: multiprofessional approach
title_full Osteopenia and osteoporosis in people living with HIV: multiprofessional approach
title_fullStr Osteopenia and osteoporosis in people living with HIV: multiprofessional approach
title_full_unstemmed Osteopenia and osteoporosis in people living with HIV: multiprofessional approach
title_sort osteopenia and osteoporosis in people living with hiv: multiprofessional approach
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/f5f865ef151a466f8e957e706f3493f5
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