Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies

Background: Vitamin A (VitA), via its active metabolite retinoic acid (RA), is critical for the maintenance of memory function with advancing age. Although its role in Alzheimer's disease (AD) is not well understood, data suggest that impaired brain VitA signaling is associated with the accumul...

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Autores principales: Essi F. Biyong, Cyntia Tremblay, Manon Leclerc, Vicky Caron, Serge Alfos, Jean-Christophe Helbling, Léa Rodriguez, Vincent Pernet, David A. Bennett, Véronique Pallet, Frédéric Calon
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/f5fc3723625a42ecb80950e796769d61
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