HYPERURICEMIA IN PRE-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS. A SINGLE CENTRE EXPERIENCE

Abstract Objective: To determine the prevalence of hyperuricemia in predialysis CKD patients in a tertiary care hospital and analyze its relationship with various socio-demographic factors. Study Design: Descriptive cross sectional study. Place and Duration of Study: Pak Emirates Military...

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Autores principales: Mohsin Qayyum, Batool Butt, Ghayas Khan
Formato: article
Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2019
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spelling oai:doaj.org-article:f606e7158faf4d8bbe43a15ff951c39b2021-11-16T02:37:41ZHYPERURICEMIA IN PRE-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS. A SINGLE CENTRE EXPERIENCE0030-96482411-8842https://doaj.org/article/f606e7158faf4d8bbe43a15ff951c39b2019-02-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2498/2053https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Abstract Objective: To determine the prevalence of hyperuricemia in predialysis CKD patients in a tertiary care hospital and analyze its relationship with various socio-demographic factors. Study Design: Descriptive cross sectional study. Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi, from 1st Jun 2017 30th Nov 2017. Material and Methods: The sample population comprised of 200 predialysis CKD patients, stage 1-5, of a tertiary care hospital in Rawalpindi, Pakistan. Fasting serum uric acid level was obtained from the patients. Relationship of age, gender, education status, marital status, smoking history, dietary history, BMI, eGFR, lipid profile and blood pressure (systolic and diastolic) was assessed with the serum uric acid level. Results: Out of 200 patients, 62.5% had hyperuricemia and 37.5% had normal levels. After applying the logistic regression we found that presence of increased systolic blood pressure, raised cholesterol level, increasing age, lowe GFR and smoking history had significant association with the hyperuricemia. Conclusion: This study showed a high prevalence of hyperuricemia in predialysis CKD patients. Special consideration should be remunerated to the predialysis CKD population having risk factors like hyperlipidemia, high systolic blood pressure along with hyperuricemia as propitious management can procrastinate the progression of CKD and eventually paring down the cardiovascular morbidity and mortality.Mohsin QayyumBatool ButtGhayas KhanArmy Medical College Rawalpindiarticleuric acidpredialysisMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 1, Pp 65-70 (2019)
institution DOAJ
collection DOAJ
language EN
topic uric acid
predialysis
Medicine
R
Medicine (General)
R5-920
spellingShingle uric acid
predialysis
Medicine
R
Medicine (General)
R5-920
Mohsin Qayyum
Batool Butt
Ghayas Khan
HYPERURICEMIA IN PRE-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS. A SINGLE CENTRE EXPERIENCE
description Abstract Objective: To determine the prevalence of hyperuricemia in predialysis CKD patients in a tertiary care hospital and analyze its relationship with various socio-demographic factors. Study Design: Descriptive cross sectional study. Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi, from 1st Jun 2017 30th Nov 2017. Material and Methods: The sample population comprised of 200 predialysis CKD patients, stage 1-5, of a tertiary care hospital in Rawalpindi, Pakistan. Fasting serum uric acid level was obtained from the patients. Relationship of age, gender, education status, marital status, smoking history, dietary history, BMI, eGFR, lipid profile and blood pressure (systolic and diastolic) was assessed with the serum uric acid level. Results: Out of 200 patients, 62.5% had hyperuricemia and 37.5% had normal levels. After applying the logistic regression we found that presence of increased systolic blood pressure, raised cholesterol level, increasing age, lowe GFR and smoking history had significant association with the hyperuricemia. Conclusion: This study showed a high prevalence of hyperuricemia in predialysis CKD patients. Special consideration should be remunerated to the predialysis CKD population having risk factors like hyperlipidemia, high systolic blood pressure along with hyperuricemia as propitious management can procrastinate the progression of CKD and eventually paring down the cardiovascular morbidity and mortality.
format article
author Mohsin Qayyum
Batool Butt
Ghayas Khan
author_facet Mohsin Qayyum
Batool Butt
Ghayas Khan
author_sort Mohsin Qayyum
title HYPERURICEMIA IN PRE-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS. A SINGLE CENTRE EXPERIENCE
title_short HYPERURICEMIA IN PRE-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS. A SINGLE CENTRE EXPERIENCE
title_full HYPERURICEMIA IN PRE-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS. A SINGLE CENTRE EXPERIENCE
title_fullStr HYPERURICEMIA IN PRE-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS. A SINGLE CENTRE EXPERIENCE
title_full_unstemmed HYPERURICEMIA IN PRE-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS. A SINGLE CENTRE EXPERIENCE
title_sort hyperuricemia in pre-dialysis chronic kidney disease patients. a single centre experience
publisher Army Medical College Rawalpindi
publishDate 2019
url https://doaj.org/article/f606e7158faf4d8bbe43a15ff951c39b
work_keys_str_mv AT mohsinqayyum hyperuricemiainpredialysischronickidneydiseasepatientsasinglecentreexperience
AT batoolbutt hyperuricemiainpredialysischronickidneydiseasepatientsasinglecentreexperience
AT ghayaskhan hyperuricemiainpredialysischronickidneydiseasepatientsasinglecentreexperience
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