Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia
A 72-year-old Japanese man was admitted to our hospital for treatment of severe COVID-19 pneumonia and was started on favipiravir, heparin calcium, and methylprednisolone pulse therapy. He recovered from respiratory failure about one month later. However, he soon developed purpura in his lower limbs...
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2021
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oai:doaj.org-article:f607decf60a040aaba9f87a3f54f22f42021-12-04T04:33:58ZDelayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia2213-007110.1016/j.rmcr.2021.101563https://doaj.org/article/f607decf60a040aaba9f87a3f54f22f42021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2213007121002252https://doaj.org/toc/2213-0071A 72-year-old Japanese man was admitted to our hospital for treatment of severe COVID-19 pneumonia and was started on favipiravir, heparin calcium, and methylprednisolone pulse therapy. He recovered from respiratory failure about one month later. However, he soon developed purpura in his lower limbs and thrombocytopenia, and immune thrombocytopenia was subsequently diagnosed. Although immune thrombocytopenia is one of the early complications of COVID-19, the use of corticosteroids for COVID-19 is thought to be a factor in the late onset of immune thrombocytopenia. In cases of severe COVID-19 for which corticosteroids were used for treatment, autoimmune diseases such as immune thrombocytopenia may manifest themselves late in the disease course.Shintaro SatoMoegi KurachiHiroki OhtaTomohiko NakamuraTomohiro ObaRie KawabeHideaki YamakawaMasako AmanoHidekazu MatsushimaElsevierarticleCOVID-19Diffuse alveolar hemorrhageImmune thrombocytopeniaPurpuraDiseases of the respiratory systemRC705-779ENRespiratory Medicine Case Reports, Vol 34, Iss , Pp 101563- (2021) |
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COVID-19 Diffuse alveolar hemorrhage Immune thrombocytopenia Purpura Diseases of the respiratory system RC705-779 |
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COVID-19 Diffuse alveolar hemorrhage Immune thrombocytopenia Purpura Diseases of the respiratory system RC705-779 Shintaro Sato Moegi Kurachi Hiroki Ohta Tomohiko Nakamura Tomohiro Oba Rie Kawabe Hideaki Yamakawa Masako Amano Hidekazu Matsushima Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia |
description |
A 72-year-old Japanese man was admitted to our hospital for treatment of severe COVID-19 pneumonia and was started on favipiravir, heparin calcium, and methylprednisolone pulse therapy. He recovered from respiratory failure about one month later. However, he soon developed purpura in his lower limbs and thrombocytopenia, and immune thrombocytopenia was subsequently diagnosed. Although immune thrombocytopenia is one of the early complications of COVID-19, the use of corticosteroids for COVID-19 is thought to be a factor in the late onset of immune thrombocytopenia. In cases of severe COVID-19 for which corticosteroids were used for treatment, autoimmune diseases such as immune thrombocytopenia may manifest themselves late in the disease course. |
format |
article |
author |
Shintaro Sato Moegi Kurachi Hiroki Ohta Tomohiko Nakamura Tomohiro Oba Rie Kawabe Hideaki Yamakawa Masako Amano Hidekazu Matsushima |
author_facet |
Shintaro Sato Moegi Kurachi Hiroki Ohta Tomohiko Nakamura Tomohiro Oba Rie Kawabe Hideaki Yamakawa Masako Amano Hidekazu Matsushima |
author_sort |
Shintaro Sato |
title |
Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia |
title_short |
Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia |
title_full |
Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia |
title_fullStr |
Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia |
title_full_unstemmed |
Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia |
title_sort |
delayed onset of severe immune thrombocytopenia associated with covid-19 pneumonia |
publisher |
Elsevier |
publishDate |
2021 |
url |
https://doaj.org/article/f607decf60a040aaba9f87a3f54f22f4 |
work_keys_str_mv |
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_version_ |
1718373007292891136 |