Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia

A 72-year-old Japanese man was admitted to our hospital for treatment of severe COVID-19 pneumonia and was started on favipiravir, heparin calcium, and methylprednisolone pulse therapy. He recovered from respiratory failure about one month later. However, he soon developed purpura in his lower limbs...

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Autores principales: Shintaro Sato, Moegi Kurachi, Hiroki Ohta, Tomohiko Nakamura, Tomohiro Oba, Rie Kawabe, Hideaki Yamakawa, Masako Amano, Hidekazu Matsushima
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Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/f607decf60a040aaba9f87a3f54f22f4
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spelling oai:doaj.org-article:f607decf60a040aaba9f87a3f54f22f42021-12-04T04:33:58ZDelayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia2213-007110.1016/j.rmcr.2021.101563https://doaj.org/article/f607decf60a040aaba9f87a3f54f22f42021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2213007121002252https://doaj.org/toc/2213-0071A 72-year-old Japanese man was admitted to our hospital for treatment of severe COVID-19 pneumonia and was started on favipiravir, heparin calcium, and methylprednisolone pulse therapy. He recovered from respiratory failure about one month later. However, he soon developed purpura in his lower limbs and thrombocytopenia, and immune thrombocytopenia was subsequently diagnosed. Although immune thrombocytopenia is one of the early complications of COVID-19, the use of corticosteroids for COVID-19 is thought to be a factor in the late onset of immune thrombocytopenia. In cases of severe COVID-19 for which corticosteroids were used for treatment, autoimmune diseases such as immune thrombocytopenia may manifest themselves late in the disease course.Shintaro SatoMoegi KurachiHiroki OhtaTomohiko NakamuraTomohiro ObaRie KawabeHideaki YamakawaMasako AmanoHidekazu MatsushimaElsevierarticleCOVID-19Diffuse alveolar hemorrhageImmune thrombocytopeniaPurpuraDiseases of the respiratory systemRC705-779ENRespiratory Medicine Case Reports, Vol 34, Iss , Pp 101563- (2021)
institution DOAJ
collection DOAJ
language EN
topic COVID-19
Diffuse alveolar hemorrhage
Immune thrombocytopenia
Purpura
Diseases of the respiratory system
RC705-779
spellingShingle COVID-19
Diffuse alveolar hemorrhage
Immune thrombocytopenia
Purpura
Diseases of the respiratory system
RC705-779
Shintaro Sato
Moegi Kurachi
Hiroki Ohta
Tomohiko Nakamura
Tomohiro Oba
Rie Kawabe
Hideaki Yamakawa
Masako Amano
Hidekazu Matsushima
Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia
description A 72-year-old Japanese man was admitted to our hospital for treatment of severe COVID-19 pneumonia and was started on favipiravir, heparin calcium, and methylprednisolone pulse therapy. He recovered from respiratory failure about one month later. However, he soon developed purpura in his lower limbs and thrombocytopenia, and immune thrombocytopenia was subsequently diagnosed. Although immune thrombocytopenia is one of the early complications of COVID-19, the use of corticosteroids for COVID-19 is thought to be a factor in the late onset of immune thrombocytopenia. In cases of severe COVID-19 for which corticosteroids were used for treatment, autoimmune diseases such as immune thrombocytopenia may manifest themselves late in the disease course.
format article
author Shintaro Sato
Moegi Kurachi
Hiroki Ohta
Tomohiko Nakamura
Tomohiro Oba
Rie Kawabe
Hideaki Yamakawa
Masako Amano
Hidekazu Matsushima
author_facet Shintaro Sato
Moegi Kurachi
Hiroki Ohta
Tomohiko Nakamura
Tomohiro Oba
Rie Kawabe
Hideaki Yamakawa
Masako Amano
Hidekazu Matsushima
author_sort Shintaro Sato
title Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia
title_short Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia
title_full Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia
title_fullStr Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia
title_full_unstemmed Delayed onset of severe immune thrombocytopenia associated with COVID-19 pneumonia
title_sort delayed onset of severe immune thrombocytopenia associated with covid-19 pneumonia
publisher Elsevier
publishDate 2021
url https://doaj.org/article/f607decf60a040aaba9f87a3f54f22f4
work_keys_str_mv AT shintarosato delayedonsetofsevereimmunethrombocytopeniaassociatedwithcovid19pneumonia
AT moegikurachi delayedonsetofsevereimmunethrombocytopeniaassociatedwithcovid19pneumonia
AT hirokiohta delayedonsetofsevereimmunethrombocytopeniaassociatedwithcovid19pneumonia
AT tomohikonakamura delayedonsetofsevereimmunethrombocytopeniaassociatedwithcovid19pneumonia
AT tomohirooba delayedonsetofsevereimmunethrombocytopeniaassociatedwithcovid19pneumonia
AT riekawabe delayedonsetofsevereimmunethrombocytopeniaassociatedwithcovid19pneumonia
AT hideakiyamakawa delayedonsetofsevereimmunethrombocytopeniaassociatedwithcovid19pneumonia
AT masakoamano delayedonsetofsevereimmunethrombocytopeniaassociatedwithcovid19pneumonia
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