Saturated fatty acids modulate cell response to DNA damage: implication for their role in tumorigenesis.

Saturated fatty acids modulate cell response to DNA damage: implication for their role in tumorigenesis.

DNA damage triggers a network of signaling events that leads to cell cycle arrest or apoptosis. This DNA damage response acts as a mechanism to prevent cancer development. It has been reported that fatty acids (FAs) synthesis is increased in many human tumors while inhibition of fatty acid synthase...

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Bibliographic Details
Main Authors: Li Zeng, Guang-Zhi Wu, Kim Jee Goh, Yew Mun Lee, Chuo Chung Ng, Ang Ben You, Jianhe Wang, Deyong Jia, Aijun Hao, Qiang Yu, Baojie Li
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/f61b9e16b56d43aba5b5ddd2df35e5b1
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