Potentiation of 17β-estradiol synthesis in the brain and elongation of seizure latency through dietary supplementation with docosahexaenoic acid

Abstract Several studies have shown that docosahexaenoic acid (DHA) attenuates epileptic seizures; however, the molecular mechanism by which it achieves this effect is still largely unknown. DHA stimulates the retinoid X receptor, which reportedly regulates the expression of cytochrome P450 aromatas...

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Auteurs principaux: Yasuhiro Ishihara, Kouichi Itoh, Miki Tanaka, Mayumi Tsuji, Toshihiro Kawamoto, Suguru Kawato, Christoph F. A. Vogel, Takeshi Yamazaki
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/f622cc0973304afc8cc9c6885c665567
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