Clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography

Mikiko Takezawa, Fumihiko Toyoda, Chiho Kambara, Hiroko Yamagami, Akihiro KakehashiDepartment of Ophthalmology, Jichi Medical University, Saitama Medical Center, Saitama, JapanBackground: To clarify the mechanism of idiopathic macular hole development, we evaluated the vitreoretinal relationship in...

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Autores principales:	Mikiko Takezawa, Fumihiko Toyoda, Chiho Kambara, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f62d195e727c4446b958d1441a09a5ef
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spelling	oai:doaj.org-article:f62d195e727c4446b958d1441a09a5ef2021-12-02T05:03:38ZClarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography1177-54671177-5483https://doaj.org/article/f62d195e727c4446b958d1441a09a5ef2011-01-01T00:00:00Zhttp://www.dovepress.com/clarifying-the-mechanism-of-idiopathic-macular-hole-development-in-fel-a6097https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Mikiko Takezawa, Fumihiko Toyoda, Chiho Kambara, Hiroko Yamagami, Akihiro KakehashiDepartment of Ophthalmology, Jichi Medical University, Saitama Medical Center, Saitama, JapanBackground: To clarify the mechanism of idiopathic macular hole development, we evaluated the vitreoretinal relationship in fellow eyes of those with a macular hole and normal eyes using spectral-domain optical coherence tomography. Thirty-one fellow eyes and 34 normal volunteer eyes without a posterior vitreous detachment (PVD) were included.Results: We classified six vitreomacular relationships: type 1, no PVD, five fellow eyes (16.1%) and nine control eyes (26.5%); type 2, shallow PVD with perifoveal vitreous attachment, seven fellow eyes (22.6%) and 19 control eyes (55.9%); type 3, shallow PVD with pinpoint foveal vitreous traction, seven fellow eyes (22.6%) and no control eyes (0%), type 4a; shallow PVD with a round defect in the posterior vitreous cortex over the perifoveal area with vitreous attachment to the perifoveal area, two fellow eyes (6.5%) and one control eye (2.9%); type 4b, shallow PVD with a round defect in the posterior vitreous cortex over the perifoveal area without vitreous attachment to the perifoveal area, no fellow eyes (0%) and one control eye (2.9%); type 5a, shallow PVD with no pseudo-operculum, no fellow eyes (0%) and four control eyes (11.8%); type 5b, shallow PVD with a pseudo-operculum, four fellow eyes (12.9%) and no control eyes (0%); and type 6, biomicroscopically relevant PVD, six fellow eyes (19.4%).Conclusion: Types 3 and 5b developed only in fellow eyes. Type 2 developed most often in normal eyes and seemed to cause less foveal stress. Type 3 may show the basic pathogenesis of macular holes. Progression of type 5b after type 3 induces abortion of developing macular holes.Keywords: idiopathic macular hole, optical coherence tomography, posterior vitreous detachment, fellow eye Mikiko TakezawaFumihiko ToyodaChiho Kambaraet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 101-108 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Mikiko Takezawa Fumihiko Toyoda Chiho Kambara et al Clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography
description	Mikiko Takezawa, Fumihiko Toyoda, Chiho Kambara, Hiroko Yamagami, Akihiro KakehashiDepartment of Ophthalmology, Jichi Medical University, Saitama Medical Center, Saitama, JapanBackground: To clarify the mechanism of idiopathic macular hole development, we evaluated the vitreoretinal relationship in fellow eyes of those with a macular hole and normal eyes using spectral-domain optical coherence tomography. Thirty-one fellow eyes and 34 normal volunteer eyes without a posterior vitreous detachment (PVD) were included.Results: We classified six vitreomacular relationships: type 1, no PVD, five fellow eyes (16.1%) and nine control eyes (26.5%); type 2, shallow PVD with perifoveal vitreous attachment, seven fellow eyes (22.6%) and 19 control eyes (55.9%); type 3, shallow PVD with pinpoint foveal vitreous traction, seven fellow eyes (22.6%) and no control eyes (0%), type 4a; shallow PVD with a round defect in the posterior vitreous cortex over the perifoveal area with vitreous attachment to the perifoveal area, two fellow eyes (6.5%) and one control eye (2.9%); type 4b, shallow PVD with a round defect in the posterior vitreous cortex over the perifoveal area without vitreous attachment to the perifoveal area, no fellow eyes (0%) and one control eye (2.9%); type 5a, shallow PVD with no pseudo-operculum, no fellow eyes (0%) and four control eyes (11.8%); type 5b, shallow PVD with a pseudo-operculum, four fellow eyes (12.9%) and no control eyes (0%); and type 6, biomicroscopically relevant PVD, six fellow eyes (19.4%).Conclusion: Types 3 and 5b developed only in fellow eyes. Type 2 developed most often in normal eyes and seemed to cause less foveal stress. Type 3 may show the basic pathogenesis of macular holes. Progression of type 5b after type 3 induces abortion of developing macular holes.Keywords: idiopathic macular hole, optical coherence tomography, posterior vitreous detachment, fellow eye
format	article
author	Mikiko Takezawa Fumihiko Toyoda Chiho Kambara et al
author_facet	Mikiko Takezawa Fumihiko Toyoda Chiho Kambara et al
author_sort	Mikiko Takezawa
title	Clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography
title_short	Clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography
title_full	Clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography
title_fullStr	Clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography
title_full_unstemmed	Clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography
title_sort	clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/f62d195e727c4446b958d1441a09a5ef
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Clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography

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