Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue
Insulin/IGF-1 signalling plays an important role in the regulation of metabolism and ageing. Here the authors show that inactivation of the pathway component PI3K p110α in the adipose tissue of mice produces a beneficial metabolic effect by enhancing β-adrenergic signalling thus energy expenditure....
Guardado en:
Autores principales: | Caroline Araiz, Anqi Yan, Lucia Bettedi, Isabella Samuelson, Sam Virtue, Anne K. McGavigan, Christian Dani, Antonio Vidal-Puig, Lazaros C. Foukas |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f62feb23d732418d85b428408797a4db |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Publisher Correction: Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue
por: Caroline Araiz, et al.
Publicado: (2020) -
Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue
por: Vanessa Pellegrinelli, et al.
Publicado: (2018) -
Regulation of p110delta PI 3-kinase gene expression.
por: Klaartje Kok, et al.
Publicado: (2009) -
NCLX prevents cell death during adrenergic activation of the brown adipose tissue
por: Essam A. Assali, et al.
Publicado: (2020) -
Role of p110a subunit of PI3-kinase in skeletal muscle mitochondrial homeostasis and metabolism
por: Mengyao Ella Li, et al.
Publicado: (2019)