Platelet CXCL4 mediates neutrophil extracellular traps formation in ANCA-associated vasculitis

Platelet CXCL4 mediates neutrophil extracellular traps formation in ANCA-associated vasculitis

Abstract Neutrophils form neutrophil extracellular traps (NETs), which are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Recent reports suggest that platelets stimulated via toll-like receptor (TLR) pathways can induce NETs formation. However, the mechanism underlying the involve...

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Autores principales: Kotaro Matsumoto, Hidekata Yasuoka, Keiko Yoshimoto, Katsuya Suzuki, Tsutomu Takeuchi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/f64033369c8343fbb1ed13579f2a4229
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