STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus

STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus

BATF is a transcription factor that is needed for IL-9 production by T helper 9 cells. Here the authors show that STAT5 is needed at the Il9 locus to enable BATF to function in this manner and that this interaction can reprogram other T helper subsets into IL-9 producing cells, thus regulating the i...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yongyao Fu, Jocelyn Wang, Gayathri Panangipalli, Benjamin J. Ulrich, Byunghee Koh, Chengxian Xu, Rakshin Kharwadkar, Xiaona Chu, Yue Wang, Hongyu Gao, Wenting Wu, Jie Sun, Robert S. Tepper, Baohua Zhou, Sarath Chandra Janga, Kai Yang, Mark H. Kaplan
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/f65e400bd7f5452ca8fba9f15ba2dcc0
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/f65e400bd7f5452ca8fba9f15ba2dcc0

Documents similaires