Spinal Cord Schistosomiasis: Diagnosis, Pathological Features and Treatment.

Background Data: Schistosomiasis affects over 200 million people worldwide. Involvement of the CNS is a rare occurrence. Spinal cord involvement is a rare manifestation of schistosomiasis, the conus medullaris being the primary site of spinal involvement. Purpose: We describe the clinical presentati...

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Autores principales:	Khaled Abdeen, Medhat Elsawy, Eman Abdelzaher
Formato:	article
Lenguaje:	EN
Publicado:	Egyptian Spine Association 2014
Materias:	spinal cord schistosomiasis bilharzial ova Schistosoma mansoni Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/f65f09e0260f4f9593fda51de89574f4
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spelling	oai:doaj.org-article:f65f09e0260f4f9593fda51de89574f42021-12-02T00:23:40ZSpinal Cord Schistosomiasis: Diagnosis, Pathological Features and Treatment.DOI:10.21608/ESJ.2014.38482314-89502314-8969https://doaj.org/article/f65f09e0260f4f9593fda51de89574f42014-01-01T00:00:00Zhttp://www.esj.journals.ekb.eg/article_3848.htmlhttps://doaj.org/toc/2314-8950https://doaj.org/toc/2314-8969Background Data: Schistosomiasis affects over 200 million people worldwide. Involvement of the CNS is a rare occurrence. Spinal cord involvement is a rare manifestation of schistosomiasis, the conus medullaris being the primary site of spinal involvement. Purpose: We describe the clinical presentation and the MRI findings of spinal cord schistosomiasis in correlation with surgery and histopatholgical findings. Study Design: Clinical case study. Patients and Methods: We report four cases of spinal cord schistosomiasis presented with rapidly progressive paraparesis associated with urinary incontinence. Three patients were males and one was female (mean age 16 years). MRI of the spine demonstrated a diffusely enhancing mass at the conus medullaris with spinal cord edema, in one of the cases, the edema extended to the upper thoracic segment. Results: In all cases, spinal masses were surgically managed through decompressive laminectomy and either biopsy or debulking. Histopathological examination showed a granulomatous inflammation surrounding bilharzial ova with a final diagnosis of spinal cord schistosomiasis. Patients were treated with Praziquantel and oral steroids. They made a remarkable neurological recovery. Conclusions: Spinal cord schistosomiasis inspite its rare occurrence, must be considered in the differential diagnosis of conus medullaris lesions. Accurate diagnosis, through recognition of its MRI appearance, allows early treatment. Better prognosis depends on decompressive laminectomy, oral steroids to abort intense immune reaction surrounding the ova and antibilharzial drug. (2014ESJ055)Khaled Abdeen Medhat ElsawyEman AbdelzaherEgyptian Spine Associationarticlespinal cord schistosomiasisbilharzial ovaSchistosoma mansoniNeurology. Diseases of the nervous systemRC346-429ENEgyptian Spine Journal, Vol 9, Iss 1, Pp 5-11 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	spinal cord schistosomiasis bilharzial ova Schistosoma mansoni Neurology. Diseases of the nervous system RC346-429
spellingShingle	spinal cord schistosomiasis bilharzial ova Schistosoma mansoni Neurology. Diseases of the nervous system RC346-429 Khaled Abdeen Medhat Elsawy Eman Abdelzaher Spinal Cord Schistosomiasis: Diagnosis, Pathological Features and Treatment.
description	Background Data: Schistosomiasis affects over 200 million people worldwide. Involvement of the CNS is a rare occurrence. Spinal cord involvement is a rare manifestation of schistosomiasis, the conus medullaris being the primary site of spinal involvement. Purpose: We describe the clinical presentation and the MRI findings of spinal cord schistosomiasis in correlation with surgery and histopatholgical findings. Study Design: Clinical case study. Patients and Methods: We report four cases of spinal cord schistosomiasis presented with rapidly progressive paraparesis associated with urinary incontinence. Three patients were males and one was female (mean age 16 years). MRI of the spine demonstrated a diffusely enhancing mass at the conus medullaris with spinal cord edema, in one of the cases, the edema extended to the upper thoracic segment. Results: In all cases, spinal masses were surgically managed through decompressive laminectomy and either biopsy or debulking. Histopathological examination showed a granulomatous inflammation surrounding bilharzial ova with a final diagnosis of spinal cord schistosomiasis. Patients were treated with Praziquantel and oral steroids. They made a remarkable neurological recovery. Conclusions: Spinal cord schistosomiasis inspite its rare occurrence, must be considered in the differential diagnosis of conus medullaris lesions. Accurate diagnosis, through recognition of its MRI appearance, allows early treatment. Better prognosis depends on decompressive laminectomy, oral steroids to abort intense immune reaction surrounding the ova and antibilharzial drug. (2014ESJ055)
format	article
author	Khaled Abdeen Medhat Elsawy Eman Abdelzaher
author_facet	Khaled Abdeen Medhat Elsawy Eman Abdelzaher
author_sort	Khaled Abdeen
title	Spinal Cord Schistosomiasis: Diagnosis, Pathological Features and Treatment.
title_short	Spinal Cord Schistosomiasis: Diagnosis, Pathological Features and Treatment.
title_full	Spinal Cord Schistosomiasis: Diagnosis, Pathological Features and Treatment.
title_fullStr	Spinal Cord Schistosomiasis: Diagnosis, Pathological Features and Treatment.
title_full_unstemmed	Spinal Cord Schistosomiasis: Diagnosis, Pathological Features and Treatment.
title_sort	spinal cord schistosomiasis: diagnosis, pathological features and treatment.
publisher	Egyptian Spine Association
publishDate	2014
url	https://doaj.org/article/f65f09e0260f4f9593fda51de89574f4
work_keys_str_mv	AT khaledabdeen spinalcordschistosomiasisdiagnosispathologicalfeaturesandtreatment AT medhatelsawy spinalcordschistosomiasisdiagnosispathologicalfeaturesandtreatment AT emanabdelzaher spinalcordschistosomiasisdiagnosispathologicalfeaturesandtreatment
_version_	1718403777495564288

Spinal Cord Schistosomiasis: Diagnosis, Pathological Features and Treatment.

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