Regulation of Key Genes for Milk Fat Synthesis in Ruminants

Milk fat is the most important and energy-rich substance in milk and plays an important role in the metabolism of nutrients during human growth and development. It is mainly used in the production of butter and yogurt. Milk fat not only affects the flavor and nutritional value of milk, but also is t...

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Autores principales:	Tong Mu, Honghong Hu, Yanfen Ma, Xiaofang Feng, Juan Zhang, Yaling Gu
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	ruminants milk fat regulatory factors genes synthesis Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/f67815e61b024fdebb9fd18ce9856fe5
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spelling	oai:doaj.org-article:f67815e61b024fdebb9fd18ce9856fe52021-11-30T23:26:15ZRegulation of Key Genes for Milk Fat Synthesis in Ruminants2296-861X10.3389/fnut.2021.765147https://doaj.org/article/f67815e61b024fdebb9fd18ce9856fe52021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fnut.2021.765147/fullhttps://doaj.org/toc/2296-861XMilk fat is the most important and energy-rich substance in milk and plays an important role in the metabolism of nutrients during human growth and development. It is mainly used in the production of butter and yogurt. Milk fat not only affects the flavor and nutritional value of milk, but also is the main target trait of ruminant breeding. There are many key genes involve in ruminant milk fat synthesis, including ACSS2, FASN, ACACA, CD36, ACSL, SLC27A, FABP3, SCD, GPAM, AGPAT, LPIN, DGAT1, PLIN2, XDH, and BTN1A1. Taking the de novo synthesis of fatty acids (FA) and intaking of long-chain fatty acids (LCFA) in blood to the end of lipid droplet secretion as the mainline, this manuscript elucidates the complex regulation model of key genes in mammary epithelial cells (MECs) in ruminant milk fat synthesis, and constructs the whole regulatory network of milk fat synthesis, to provide valuable theoretical basis and research ideas for the study of milk fat regulation mechanism of ruminants.Tong MuHonghong HuYanfen MaXiaofang FengJuan ZhangYaling GuFrontiers Media S.A.articleruminantsmilk fatregulatory factorsgenessynthesisNutrition. Foods and food supplyTX341-641ENFrontiers in Nutrition, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	ruminants milk fat regulatory factors genes synthesis Nutrition. Foods and food supply TX341-641
spellingShingle	ruminants milk fat regulatory factors genes synthesis Nutrition. Foods and food supply TX341-641 Tong Mu Honghong Hu Yanfen Ma Xiaofang Feng Juan Zhang Yaling Gu Regulation of Key Genes for Milk Fat Synthesis in Ruminants
description	Milk fat is the most important and energy-rich substance in milk and plays an important role in the metabolism of nutrients during human growth and development. It is mainly used in the production of butter and yogurt. Milk fat not only affects the flavor and nutritional value of milk, but also is the main target trait of ruminant breeding. There are many key genes involve in ruminant milk fat synthesis, including ACSS2, FASN, ACACA, CD36, ACSL, SLC27A, FABP3, SCD, GPAM, AGPAT, LPIN, DGAT1, PLIN2, XDH, and BTN1A1. Taking the de novo synthesis of fatty acids (FA) and intaking of long-chain fatty acids (LCFA) in blood to the end of lipid droplet secretion as the mainline, this manuscript elucidates the complex regulation model of key genes in mammary epithelial cells (MECs) in ruminant milk fat synthesis, and constructs the whole regulatory network of milk fat synthesis, to provide valuable theoretical basis and research ideas for the study of milk fat regulation mechanism of ruminants.
format	article
author	Tong Mu Honghong Hu Yanfen Ma Xiaofang Feng Juan Zhang Yaling Gu
author_facet	Tong Mu Honghong Hu Yanfen Ma Xiaofang Feng Juan Zhang Yaling Gu
author_sort	Tong Mu
title	Regulation of Key Genes for Milk Fat Synthesis in Ruminants
title_short	Regulation of Key Genes for Milk Fat Synthesis in Ruminants
title_full	Regulation of Key Genes for Milk Fat Synthesis in Ruminants
title_fullStr	Regulation of Key Genes for Milk Fat Synthesis in Ruminants
title_full_unstemmed	Regulation of Key Genes for Milk Fat Synthesis in Ruminants
title_sort	regulation of key genes for milk fat synthesis in ruminants
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/f67815e61b024fdebb9fd18ce9856fe5
work_keys_str_mv	AT tongmu regulationofkeygenesformilkfatsynthesisinruminants AT honghonghu regulationofkeygenesformilkfatsynthesisinruminants AT yanfenma regulationofkeygenesformilkfatsynthesisinruminants AT xiaofangfeng regulationofkeygenesformilkfatsynthesisinruminants AT juanzhang regulationofkeygenesformilkfatsynthesisinruminants AT yalinggu regulationofkeygenesformilkfatsynthesisinruminants
_version_	1718406237908893696

Regulation of Key Genes for Milk Fat Synthesis in Ruminants

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